Single|cell transcriptomic profiling reveals a pathogenic role of ...

Single-cell transcriptomic profiling reveals a pathogenic role of ...

Giant cell arteritis (GCA) is a systemic vasculitis mediated by an aberrant immunological response against the blood vessel wall.

Single-cell transcriptomic profiling reveals a pathogenic role of ...

In addition, effector regulatory T cells (Tregs) were decreased in GCA and showed lower expression of genes involved in their suppressive activity. These ...

Single-cell transcriptomic profiling reveals a pathogenic role of ...

Single-cell transcriptomic profiling reveals a pathogenic role of cytotoxic CD4+ T cells in giant cell arteritis · No full-text available · Citations (2) ...

Single-cell RNA sequencing reveals the pro-inflammatory roles of ...

We reveal that cholangiocytes and hepatic stellate cells are involved in liver inflammation and fibrosis.

Single-cell transcriptomic profiles in the pathophysiology within the ...

Advanced single-cell RNA sequencing (scRNA-seq) could reveal the complex architecture and interaction with the microenvironment in early DKD. We ...

Single-cell transcriptome profiling reveals immune and stromal cell ...

In the inflamed glandular tissues, CD4+ effector subpopulations (e.g., Th1 cells, Th17 cells) contribute to pathogenesis by producing pro- ...

Single-cell transcriptomics reveal potent extrafollicular B cell ...

Type I IFN is recognised as a central mediator in the pathogenesis of SLE. A high baseline IFN signature is associated with earlier development ...

Single-cell multi-omics analysis reveals IFN-driven alterations in T ...

Differential expression analysis confirmed a distinct cytotoxic profile in comparison with other CD4 + T cells, including elevated expression of canonical T ...

Single-Cell Transcriptome Profiling Reveals the Suppressive Role of ...

Here, we performed scRNA-seq on the retina of non-human primates with diabetes mellitus, and identified cell-type-specific molecular changes of ...

Spatiotemporal single‐cell transcriptomic profiling reveals ...

Spatiotemporal single-cell transcriptomic profiling reveals inflammatory cell states in a mouse model of diffuse alveolar damage.

Transcriptomic Profiling Reveals Intense Host-Pathogen Dispute ...

Transcriptomic profiling at single-cell resolution would make it possible to discriminate the innate immune responses of RVFV-infected cells ...

Single-cell RNA-seq reveals cell type–specific molecular and ...

Bulk transcriptomic profiling has implicated increased type 1 interferon signaling, dysregulated lymphocyte activation, and failure of apoptotic ...

Single-cell transcriptome analysis and protein profiling reveal broad ...

Previous studies have revealed that cytotoxic T subtypes, especially CD4+ CTLs, play an important role in the pathogenesis of IgG4-RD. These ...

Understanding the pathogenesis of infectious diseases by single ...

Transcriptional profiling at the single-cell level enables the analysis of cell diversity, heterogeneity of the immune response, and detailed molecular ...

Single-cell transcriptomic profiling reveals distinct mechanical ...

The single cell transcriptomic profiling of TPCs and their subsets serves as a foundation for further investigation into the pathology and ...

Single-cell RNA-seq reveals transcriptomic heterogeneity mediated ...

Single-cell RNA sequencing highlights the influence of host–pathogen interactions and stochasticity on transcriptional and phenotypic ...

Current Status and Prospects of the Single-Cell Sequencing ... - MDPI

Single-cell RNA sequencing (scRNA-seq) is a method that focuses on the analysis of gene expression profile in individual cells.

Transcriptomic profiling of immune cells in murine polymicrobial sepsis

Single-cell RNA sequencing (scRNA-seq) enables comprehensive transcriptome profiling and unbiased cell classification. In this study, we have unveiled the ...

a Paradigm for Investigation of Systemic Host-Pathogen Interactions

Transcriptomic analyses revealed several distinct patterns of gene expression over time, with many immune-related genes showing sustained levels ...

Single-cell analysis to understand the diversity of immune cell types ...

Single-cell next-generation sequencing assays are powerful tools to understand the nature of the immune cells that drive disease pathogenesis.