Single Cell Transcriptome Helps Better Understanding Crosstalk in ...

Years of research revealed that crosstalk extensively existed among kidney cells, cell factors and metabolites and played an important role ...

In the last few years, single-cell RNA sequencing (scRNA-seq) technology provided new insight into cellular heterogeneity and genetic susceptibility regarding ...

Single Cell Transcriptome Helps Better Understanding Crosstalk in ...

Years of research revealed that crosstalk extensively existed among kidney cells, cell factors and metabolites and played an important role in the ...

Single-cell Transcriptome and Crosstalk Analysis Reveals Immune ...

Article. Single-cell Transcriptome and Crosstalk Analysis Reveals Immune Alterations and Key Pathways in the Bone Marrow of Knee Osteoarthritis ...

Single Cell Transcriptome Helps Better Understanding Crosstalk in ...

Single Cell Transcriptome Helps Better Understanding Crosstalk in Diabetic Kidney Disease. Du, C.; Ren, Y.; Li, G.; Yang, Y.; Yan, Z.; Yao, F. Frontiers in ...

Single-cell transcriptomics uncover hub genes and cell–cell ...

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful scientific method which grew as an alternative to traditional bulk RNA sequencing (RNA-seq) ...

Single-cell transcriptome and crosstalk analysis reveals immune ...

We employed robust analytical pipelines to evaluate changes in cell population abundances, identify differentially expressed genes, and cell-cell signaling ...

Advances in single-cell RNA sequencing and its applications in ...

In human cancer research, scRNA-seq has been widely used to study heterogeneity, the TME, gene expression profiles, transcriptome profiles, and ...

Single-cell transcriptomics analysis of bullous pemphigoid unveils ...

Herein, using single-cell RNA sequencing (scRNA-seq) and in vitro functional analyzes, we pinpoint Th2 cells, dendritic cells (DCs), and ...

Single-cell transcriptomic architecture and intercellular crosstalk of ...

ICC typically features remarkable cellular heterogeneity and a dense stromal reaction. Therefore, a comprehensive understanding of cellular ...

Comparison of methods and resources for cell-cell communication ...

The growing availability of single-cell data, especially transcriptomics, has sparked an increased interest in the inference of cell-cell ...

Single-cell RNA-sequencing analysis of immune and mesenchymal ...

(A) UMAP plot of all cells pooled and integrated from tendon entheses at postnatal day 11 (P11), P18, and P56, including both immune cell populations and ...

Harnessing Single-Cell RNA Sequencing to Better Understand How ...

Single-cell transcriptome analysis including unsupervised computational methods (PCA, t-SNE, or UMAP) can cluster cells into unique populations ...

Applications of single-cell sequencing in cancer research: progress ...

Split-seq, which is based on Sci-Seq, utilizes 5 rounds of barcoding, which significantly improves sequencing over millions of single cells and ...

Single-Cell RNA Sequencing and Combinatorial Approaches for ...

These single-cell transcriptome and ... This integrated approach helped improve our understanding of leucocyte diversity and dynamics in atherosclerosis.

New avenues for systematically inferring cell-cell communication

Drawing upon the latest development of single-cell RNA-sequencing (scRNA-seq), high-resolution transcriptomic data have deepened our ...

Integration of spatial and single-cell transcriptomics localizes ...

Integration of the single-cell sequencing with spatial transcriptomics improves power and enables in situ visualization of signatures with ...

Single cell analysis reveals immune cell–adipocyte crosstalk ... - eLife

Therefore, a better understanding of the mechanisms controlling adipose thermogenesis could inform the development of new therapies for ...

Deciphering Innate Immune Cell-Tumor Microenvironment Crosstalk ...

Understanding the role of each player in TME, especially at a single-cell level, can help us better establish the knowledge network and ...

Single‐cell RNA sequencing in breast cancer: Understanding tumor ...

One example is the in situ 10-cell RNA-seq (10cRNA-seq) [20], which combines the single-cell resolution of laser capture and improves the ...