Single Daily Dose of Ceftriaxone for Bacterial Meningitis in Adults

A single daily dose of ceftriaxone for bacterial meningitis in adults

We used a single daily dose of ceftriaxone (50 mg/[kg.d]; maximum, 4 g/d) for the treatment of bacterial meningitis in 84 adult patients.

Ceftriaxone dosing, indications, interactions, adverse effects, and more

... meningitis is documented, treat for 10-14 days; Prophylaxis for infants of ... single daily dose for 7 days; daily dose not to exceed 1 g; >45 kg with ...

A Single Daily Dose of Ceftriaxone for Bacterial Meningitis in Adults

Both our experience and that in the literature suggest that a single daily dose is optimal when ceftriaxone is used for the treatment of bacterial meningitis.

Treatment of bacterial meningitis with once daily ceftriaxone therapy

Ceftriaxone, a cephalosporin with an extended half-life and excellent antibacterial activity was used to treat bacterial meningitis, given as a single daily ...

Ceftriaxone Dosage Guide + Max Dose, Adjustments - Drugs.com

The total daily dose should not exceed 4 g. Uses: For the treatment of the following infections when due to susceptible organisms: Bacterial ...

Single Daily Dose of Ceftriaxone for Bacterial Meningitis in Adults

Although the pharmacokinetics of ceftriaxone allows its administration in a single daily dose, this practice is not standard in the treatment of bacterial ...

Ceftriaxone | Johns Hopkins ABX Guide

USUAL ADULT DOSING · Ceftriaxone (CTX) for most infections: 1-2 g IM or IV q24h. Maximum daily dose: 4 g/day · Meningitis: 2 g IV q12h ...

should we be using once- or twice-daily dosing for meningitis ...

Guidelines for bacterial meningitis in children recommend intravenous ceftriaxone 50 mg/kg (max 2 g) twice daily (BD) or 100 mg/kg (max 4 g) ...

Ceftriaxone Dosing: Once or Twice Daily? - Contagion Live

... treatment of bacterial meningitis is 4 grams divided once or twice daily. 9 Subsequent literature has demonstrated that a once daily dose is ...

Ceftriaxone-AFT, Powder for injection - Medsafe

The recommended adult daily dose is 1-2 g given once daily or in ... doses in paediatric patients suffering from bacterial meningitis are shown in ...

Ceftriaxone Prescription & Dosage Information - MPR - eMPR.com

Skin and skin structures: may give once daily or in 2 equally divided doses every 12hrs; max 2g/day. Meningitis: 100mg/kg (max 4g) for 1 dose, then 100mg/kg per ...

Ceftriaxone: Side Effects, Uses, Dosage, Interactions, Warnings

Adult: 2 g intravenously (IV) every 12 hours for 7-14 days · Pediatric: 100 mg/kg/day intravenously/intramuscularly (IV/IM) in single daily dose or divided every ...

Meningitis Treatment & Management - Medscape Reference

In areas with a low prevalence of DRSP, cefotaxime or ceftriaxone plus ampicillin is recommended. Pediatric dosing is as follows: Cefotaxime – ...

Rocephin (Ceftriaxone): Side Effects, Uses, Dosage ... - RxList

For the treatment of acute bacterial otitis media, a single intramuscular dose of 50 mg/kg (not to exceed 1 gram) is recommended (see INDICATIONS). For the ...

Single- vs Divided-Dose Ceftriaxone Therapy for Meningitis

2. Congeni BL, Bradley J, Hammerschlag MR: Safety and efficacy of once daily ceftriaxone for the treatment of bacterial meningitis . Pediatr ...

Fatal Bacterial Meningitis Possibly Associated with Substandard ...

Once-daily treatment with 2 g of intravenous ceftriaxone administered according to guidelines failed, and the patient died. ... This would have ...

Results of a Swiss multicenter study. Part I: Clinical results | Infection

The results of this study suggest that short course treatment of acute bacterial meningitis in children with single daily ceftriaxone monotherapy is as ...

Ceftriaxone for Injection, USP - accessdata.fda.gov

a 75 mg/kg IV dose in pediatric patients suffering from bacterial meningitis ... For the treatment of acute bacterial otitis media, a single intramuscular dose.

Ceftriaxone | Drugs | BNF - NICE

2–4 g once daily, doses at the higher end of the recommended range used in severe cases. By deep intramuscular injection. Adult: 2 g once daily, increased if ...

High-Dose Ceftriaxone for Bacterial Meningitis and Optimization of ...

Recommended ceftriaxone dosages for treating meningitis are different from one learned society to another. The IDSA (Infectious Diseases Society ...