Six years of mainstreaming germline genetic testing across cancer ...

Mainstreaming is an updated model where non-genetics clinicians (ie, oncologists) order GT for select patients, with genetics professionals involved only for ...

Mainstreaming is an updated model where non-genetics clinicians (ie, oncologists) order GT for select patients, with genetics professionals involved only for ...

Six years of mainstreaming germline genetic testing across cancer ...

A micro-costing and cost-effectiveness analysis of genome sequencing vs exome sequencing in pediatric rare diseases. Wendy Ungar1, Vercancy Wu1, ...

Mainstream Germline Genetic Testing with Expanded Eligibility for ...

Mainstream genetic testing of breast cancer patients facilitated by BCCs makes it feasible for a large health care system to expand germline ...

Few People with Cancer Undergo Germline Testing - NCI

Among the more than 1.3 million people in the study, only about 93,000, or 6.8%, underwent germline genetic testing through March 31, 2021, ...

Mainstream germline genetic testing in men with metastatic prostate ...

In international guidelines, germline genetic testing is recommended for patients with metastatic prostate cancer. Before undergoing germline ...

Germline Genetic Testing After Cancer Diagnosis - JAMA Network

The rates of testing increased over time, particularly for patients with pancreatic cancer (from 1.2% in 2013 to 18.6% in 2019). Testing ...

Selection of Germline Genetic Testing Panels in Patients With Cancer

These multigene panels include genes in which pathogenic or likely pathogenic variants confer a high relative risk of cancer (BRCA1/2 and Lynch ...

Mainstreaming of Genetic Testing Is Tied to Increased Testing Rates ...

Findings showed that among 1742 patients, 91.3% underwent genetic germline testing vs 8.6% who did not undergo testing. Read more. Ovarian ...

Mainstreaming germline genetic testing for patients with pancreatic ...

From September 2019 until April 2021, 241 patients underwent genetic testing through this mainstreaming program. An additional 4 patients ...

Germline Testing in Patients With Breast Cancer - ASCO Publications

Until broad multigene panels became more widely available and affordable, testing for germline mutations in breast cancer susceptibility genes ...

Mainstream germline genetic testing for patients with epithelial ...

With mainstream genetic testing, genetic testing is offered more often after diagnosis to patients with ovarian cancer. · Genetics-related ...

Comparison of Germline Genetic Testing Before and After a Medical ...

This cohort study of claims data examines whether uptake of microsatellite instability and/or immunohistochemistry tumor screening germline ...

The Feasibility of Implementing Mainstream Germline Genetic ...

In a mainstream genetic testing pathway, non-genetic healthcare professionals (NGHCPs) provide pre-test counseling (e.g., review cancer family history, discuss ...

Guidelines for genetic testing in prostate cancer: a scoping review

... over the next 10 years [6]. Personalised prevention and treatment ... Genetic testing, including germline testing of hereditary cancer ...

Mainstream genetic testing for women with ovarian cancer provides ...

Genetic testing for patients with ovarian cancer has increased over the years, due to expanding eligibility criteria and individualized ...

Germline Testing in Prostate Cancer: When and Who to Test

If a germline mutation was identified, the patient was referred to a genetic counselor to discuss the further implications of the results and to ...

An Australian mainstream genetic testing program: Clinicians views ...

Germline genetic testing results can guide treatment decisions for oncology patients and are now offered to many cancer patients. Mainstream ...

Mainstreaming germline genetic testing for patients with pancreatic ...

We implemented a mainstreaming program in oncology clinics to increase testing for PC patients. Genetic counselors trained oncology providers to ...

Commentary: Why is genetic testing underutilized worldwide? The ...

Despite increasing awareness of the genetic basis of cancer and our evolving knowledge of effective means of prevention, screening, and ...