Size|dependent protein segregation at membrane interfaces

Size-dependent protein segregation at membrane interfaces - Nature

Size-dependent protein segregation in biology. Our experiments and simulations show that protein size is a simple, sensitive, and highly ...

Size-dependent protein segregation at membrane interfaces - NCBI

We show that size differences between binding and non-binding proteins can dramatically alter their organization at membrane interfaces in the ...

Size-dependent protein segregation at membrane interfaces - ORA

We reconstituted membrane interfaces in vitro using giant unilamellar vesicles decorated with synthetic binding and non-binding proteins.

Size-dependent protein segregation at membrane interfaces

We show that size differences between membrane proteins can drastically alter their organization at membrane interfaces, with as little as a ∼5 nm increase in ...

Size Matters: Protein Segregation at Membrane Interfaces

The ability of two membranes to interact with each other is highly dependent on the proteins that are located on the surface of the membranes.

Size-dependent protein segregation at membrane interfaces

Schmid, Eva M. ; Bakalar, Matthew H. ; Choudhuri, Kaushik ; Weichsel, Julian ; Ann, Hyoung Sook ; Geissler, Phillip L. ; Dustin, Michael L. ; Fletcher, ...

Size-dependent protein segregation creates a spatial switch for ...

a, A schematic showing spatial distribution of Notch signaling components at the juxtaposed cell-cell interface. b, Representative confocal ...

Engineering Functional Membrane–Membrane Interfaces by InterSpy

... protein between the membranes is strictly dependent on SpyTag/SpyCatcher. ... membrane protein sorting and size-exclude large proteins. While ...

Binding and segregation of proteins in membrane adhesion

The proteins can only bind if the separation between apposing membranes is sufficiently close to the length of the protein complexes, which leads to an ...

An investigation of the effect of membrane curvature on ...

... membrane curvature on transmembrane-domain dependent protein sorting ... proteins are involved in TMD-dependent sorting at the ER-Golgi interface. It ...

Size-Dependent Segregation Controls Macrophage Phagocytosis of ...

To quantify the ability of the membrane interface to exclude large proteins, we again turned to GMPVs and generated interfaces between GPMVs and ...

Membrane structure and assembly articles within Nature Physics

Size-dependent protein segregation at membrane interfaces. Segregation between binding and non-binding proteins in the space between cells is critical for ...

The more the merrier: effects of macromolecular crowding on the ...

The diffusion coefficients were inversely proportional to the peripheral protein density at the membrane interface rather than the size of the ...

Protein sorting at the ER–Golgi interface | Journal of Cell Biology

... membrane barriers without perturbing the functional segregation ... M. Rape . 2012 . Ubiquitin-dependent regulation of COPII coat size and ...

Engineering functional membrane-membrane interface by InterSpy

... Size-dependent protein segregation at membrane interfaces. Nature Physics 2016 12:7, 12 (7), 704–711. 31. Kirkton, R.D., and Bursac, N ...

Low membrane fluidity triggers lipid phase separation and protein ...

Lipid phase separation drives segregation of membrane proteins into the fluid phase and severely limits and confines lateral diffusion of ...

Claudin-4 reconstituted in unilamellar vesicles is sufficient to form ...

Cldn4–Cldn4 interfaces drive the segregation of membrane-bound proteins. (A) ... D. A.. (. 2016. ). Size-dependent protein segregation at membrane interfaces .

An investigation of the effect of membrane curvature on ...

An investigation of the effect of membrane curvature on transmembrane-domain dependent protein sorting in lipid bilayers ... protein sorting at the interface ...

Cell-cell interfaces NRMCB manuscript revision draft for Oxford]

Size-dependent protein segregation at membrane interfaces. Nat. Phys. 12, 704–711 (2016). 25. Farquhar, M. G. & Palade, G. E. Junctional complexes in ...

A Mammalian-Based Synthetic Biology Toolbox to Engineer ...

... Size-dependent protein segregation at membrane interfaces. Nat Phys 12:704–711; Belardi B, Son S, Vahey MD et al (2019) Claudin-4 reconstituted in ...