Size|dependent protein segregation creates a spatial switch for ...

Size-dependent protein segregation creates a spatial switch for ...

Size-dependent protein segregation creates a spatial switch for Notch signaling and function · Find this author on Google Scholar · Find this ...

Size-dependent protein segregation creates a spatial switch for ...

We report that size-dependent protein segregation acts as a spatial switch regulating the dynamic distribution of these receptors relative to their enzymatic ...

(PDF) Size-dependent protein segregation creates a spatial switch ...

PreprintPDF Available. Size-dependent protein segregation creates a spatial switch for Notch and APP signaling. June 2020. DOI:10.1101/2020.06.28.176560.

Size-dependent protein segregation creates a spatial switch for ...

... space and time is unclear. Here, we report that cadherin ... Size-dependent protein segregation creates a spatial switch for Notch signaling and function.

bioRxiv on X: "Size-dependent protein segregation creates a spatial ...

Size-dependent protein segregation creates a spatial switch for Notch and APP signaling https://t.co/0S9Bbe3Lgr #bioRxiv.

(PDF) Size-dependent protein segregation creates a spatial switch ...

Size-dependent protein segregation creates a spatial switch for Notch signaling and function ... Aberrant cleavage of Notch by γ-secretase is implicated in ...

Size-dependent protein segregation at membrane interfaces - NCBI

We show that size differences between binding and non-binding proteins can dramatically alter their organization at membrane interfaces.

A particle size threshold governs diffusion and segregation of PAR-3 ...

Intuitively, for cortical flows to effectively segregate a membrane-bound protein, the cortical flow must dominate the randomization of particle ...

The cadAJ-mediated spatial switch regulates Notch and APP ...

a, Representative from publication: Size-dependent protein segregation creates a spatial switch ... Size-dependent protein segregation creates a spatial switch ...

Spatial control of Draper receptor signaling initiates apoptotic cell ...

However, as the clusters mature, but well before they reach the central synapse, the microclusters deplete F-actin to create “holes” in the actin cytoskeleton.

Design principles for selective polarization of PAR proteins by ...

Clustering of membrane-associated molecules is thought to promote interactions with the actomyosin cortex, enabling size-dependent transport ...

Spatial control of irreversible protein aggregation - eLife

A theoretical basis for the spatial regulation of protein aggregation shows how aggregates can partition preferentially into intracellular ...

Membrane compartmentalization by adherens junctions creates a ...

suggesting the essential role of size-dependent protein segregation as a spatial switch to direct Notch activation. The substantial NICD ...

Spatial segregation between cell–cell and cell–matrix adhesions

Spatial segregation of CMA and CCA seems to act as and/or result from a major morphogenetic force shaping cells and tissues. Although this segregation has been ...

Membrane compartmentalization by adherens junctions creates a ...

... proteins regulating development ... Biology. TLDR. An unprecedented role of AJs is suggested in creating size-selective spatial switches ...

Restricted access: spatial sequestration of damaged proteins during ...

Such spatial sequestration and asymmetric segregation of damaged proteins have emerged as key processes required for cellular rejuvenation. In ...

Full article: Spatial regulation of coalesced protein assemblies

Thus most organisms have cellular mechanisms that spatially constrain protein aggregates to a single deposit ( Fig. 1A ), which for example enables the ...

Distinct segregation patterns of yeast cell-peripheral proteins ...

We surmise that protein segregation plays a crucial role in regulating various biological processes, such as polarized cell growth and cellular ...

Reconstitution of self-organizing protein gradients as spatial cues in ...

Moreover, we show that compartment geometry plays a major role in Min gradient establishment, and provide evidence for a geometry-mediated ...

Boltzmann Energy-based Image Analysis Demonstrates that ... - PLOS

We conclude that energy processes implicit in protein size based segregation can drive the patternation observed in individual synapses, at least for the ...