Small Molecules for Neurodegeneration Applications

Small Molecules for Neurodegeneration Applications - EMD Millipore

Small Molecules for Neurodegeneration Applications · Amyloidogenesis Inhibitors · Cholinesterase Inhibitors · Monoamine Oxygenase (MAO) Inhibitors · Secretase ...

Small Molecules: Therapeutic Application in Neuropsychiatric and ...

Small Molecules: Therapeutic Application in Neuropsychiatric and Neurodegenerative Disorders · Abstract. In recent years, an increasing number of ...

Small Molecules for neurodegenerative disease - Patsnap Synapse

Unlike directly targeting neurodegenerative proteins, another strategy uses small molecule drugs against their encoding RNAs. For example ...

Small molecules to perform big roles: The search for Parkinson's ...

The motor symptoms described in PD are triggered by the neurodegeneration of dopaminergic neurons, partly due to an accumulation of intraneuronal abnormal alpha ...

Recent progress and applications of small molecule inhibitors of ...

It has garnered significant attention as a potential therapeutic target for neurodegenerative diseases (NDD). Although progress has been ...

Application of Small Molecules in the Central Nervous System Direct ...

The use of small molecules to directly reprogram somatic cells into neurons provides a new therapeutic strategy for neurological diseases. In this review, the ...

Potential of Therapeutic Small Molecules in Apoptosis Regulation in ...

Neurodegenerative diseases (NDs) are a group of diseases that are commonly characterized by the slow progressive loss of neurons in the central nervous system ( ...

A novel class of drug candidates for neurodegenerative diseases

The technology combines two highly selective molecules, each of which was individually designed to target and disrupt pathological forms of ...

Current Small Molecule–Based Medicinal Chemistry Approaches for ...

Neurodegenerative diseases (NDDs) like Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic lateral sclerosis (ALS) are ...

Mitochondria-affecting small molecules ameliorate proteostasis ...

Defects in mitochondrial clearance have long been linked to diminished physiological function and neurodegenerative diseases (as reviewed in).

Small molecule enhancers of autophagy for neurodegenerative ...

Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, prion diseases and ...

Development of small molecules for disrupting pathological amyloid ...

Developing small molecules is on the host spot of the research field searching therapies for neurodegenerative diseases. The capabilities of ...

Small molecule inhibitors of α-synuclein oligomers identified by ...

Parkinson's disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein ...

Small Molecules and Peptides Targeting Glial Cell Line-Derived ...

The current review will describe peptides and small molecules mimicking the biological effects of GFLs in cultured cells and animal models of relevant ...

Small‐Molecule Theranostic Probes: A Promising Future in ...

Several diagnostic imaging probes have been developed to monitor cerebral amyloid lesions in patients with neurodegenerative disorders (such as ...

Derivation and Expansion Using Only Small Molecules of Human ...

Here, we report the derivation and propagation using only small molecules of human neural progenitor cells (small molecule neural precursor cells; smNPCs).

(PDF) Small Molecules: Therapeutic Application in Neuropsychiatric ...

However, interesting data on possible therapeutic applications of small molecules for the treatment of neuropsychiatric and neurodegenerative ...

Recent advancements in chromone as a privileged scaffold towards ...

In this short review, we focused on the recent advancements and developments of chromones for neurodegenerative therapeutics. Different small molecules were ...

Transdifferentiation: a new promise for neurodegenerative diseases

Can the efficiency of ciN generation from adult human somatic cells be improved for further translational applications? Can small molecules or ...

Small-molecule Hsp90 Inhibitors: Applications in Cancer and ...

Heat Shock Proteins in Cancer; Chapter. Small-molecule Hsp90 Inhibitors: Applications in Cancer and Neurodegenerative diseases. Chapter. pp 275–294; Cite this ...