Somatic Cell Gene Editing
Probably the best known example is sickle-cell disease, which is caused by a variation in one of the genes encoding hemoglobin, the protein that carries oxygen ...
The Somatic Cell Genome Editing (SCGE) program created high-quality tools for safe and effective genome editing in humans and made these tools widely available ...
The NIH Somatic Cell Genome Editing program - Nature
The move from reading to writing the human genome offers new opportunities to improve human health. The United States National Institutes of ...
Somatic genome editing: an overview - PHG Foundation
Genome editing can be performed in germline cells (sperm, eggs or embryos) to induce heritable genetic changes or in somatic cells (other cells) to induce non- ...
Somatic Gene Therapy - an overview | ScienceDirect Topics
Somatic cell gene therapy involves the placement of a human gene into a living person's somatic cells—cells that do not produce the eggs and sperm that in turn ...
Genome editing can be performed in germline cells (sperm, eggs or embryos) to induce heritable genetic changes or in somatic cells (other cells) to induce ...
Program Snapshot. The goal of the SCGE program is to accelerate the development of genome editing therapies into the clinic. For Phase 2, there ...
NIH Common Fund Somatic Cell Genome Editing Program - YouTube
For more information on the Somatic Cell Genome Editing program, visit our website at: https://commonfund.nih.gov/editing Follow this link ...
The history, use, and challenges of therapeutic somatic cell and ...
Editing or modifying the genome of gametes or embryos as a means to correct disease-causing mutations in all subsequent generations also became possible. Both ...
One small edit for humans, one giant edit for humankind? Points and ...
Beyond safety issues, somatic gene editing in humans does raise ethical, legal and social issues (ELSI), however, it is suggested to be less ...
Advancing therapeutic gene editing - The Jackson Laboratory
Somatic cells are any of the non-reproductive cells of the body, i.e. the cells that do not pass DNA down to the next generation. By focusing on ...
The NIH Somatic Cell Genome Editing program. - Scholars@Duke
The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium aims to accelerate the development of safer and more- ...
Home | SCGE Toolkit - Somatic Cell Gene Editing
SCGE Somatic Cell Genome Editing (SCGE) Toolkit. The goal of the Somatic Cell Genome Editing (SCGE) program is to accelerate the development of safer and more ...
Key challenges in bringing CRISPR-mediated somatic cell therapy ...
Genome editing using clustered regularly interspersed short palindromic repeats (CRISPR) and CRISPR-associated proteins offers the potential ...
Editorial: Somatic Cell Gene Editing for Treating Diseases - Frontiers
This article is part of the Research Topic Somatic Cell Gene Editing for Treating Diseases. View all 7 articles.
Why treat gene editing differently in two types of human cells?
Somatic therapies target genes in specific types of cells (lung cells, skin cells, blood cells, etc), while germline modifications, applied to ...
Center for Somatic Cell Genome Editing: Home Page
Main navigation ... The NIH Center for Somatic Cell Genome Editing (CSGE) in Nonhuman Primates was established to provide collaborative ...
The NIH Somatic Cell Genome Editing program | NIST
The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium aims to accelerate the development of safer ...
Somatic genome editing therapies are becoming a reality
“Somatic” genome editing (which makes changes that are not heritable) is different to germline and heritable genome editing (which makes ...
The NIH Somatic Cell Genome Editing program - OSTI.GOV
The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium aims to accelerate the development of safer and more- ...