Staphylococcus aureus major cell division protein FtsZ assembly is ...

The bacterial cell division protein FtsZ has been considered a potential therapeutic target due to its rapid treadmilling that induces ...

The current study discovered a novel antimicrobial compound, silibinin, a natural flavonolignan and its impact on the recombinant S. aureus FtsZ (SaFtsZ).

An essential Staphylococcus aureus cell division protein directly ...

When a bacterium is preparing to divide, filaments made of a protein called FtsZ form a ring at the site where the cell will split. Many other ...

Staphylococcus aureus major cell division protein FtsZ assembly is ...

Staphylococcus aureus major cell division protein FtsZ assembly is inhibited by silibinin, a natural flavonolignan that also blocked bacterial growth and ...

An essential Staphylococcus aureus cell division protein directly ...

GpsB in Staphylococcus aureus directly regulates the central cell division protein FtsZ, a different function from that assigned for GpsB in ...

3VOB: Staphylococcus aureus FtsZ with PC190723 - RCSB PDB

FtsZ is a key molecule in bacterial cell division. In the presence of GTP, it polymerizes into tubulin-like protofilaments by head-to-tail ...

Complex state transitions of the bacterial cell division protein FtsZ

Using molecular dynamics simulations, the authors discovered that Staphylococcus aureus FtsZ can exist in multiple stable states, with closed- ...

Cell constriction requires processive septal peptidoglycan synthase ...

Here using single-molecule imaging of division proteins in the Gram-positive pathogen Staphylococcus aureus, we showed that the septal PG ...

Cell division protein FtsZ - Staphylococcus aureus | UniProtKB

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly ...

Nucleotide‐induced folding of cell division protein FtsZ ... - FEBS Press

FtsZ is a structural homolog of tubulin and a target for discovering new antibiotics. Here, using FtsZ from the pathogen S. aureus (SaFtsZ), we ...

An Essential Staphylococcus aureus Cell Division Protein directly ...

When a bacterium is preparing to divide, filaments made of a protein called FtsZ form a ring at the site where the cell will split. Many other ...

Cell Division Protein FtsZ: From Structure and Mechanism to ...

In most bacteria including Firmicutes and Proteobacteria, the NTP has not yet been assigned a decided function; however, in cyanobacteria, it is highly ...

Staphylococcus aureus FtsZ and PBP4 bind to the conformationally ...

In the Firmicutes phylum, GpsB is a membrane associated protein that coordinates peptidoglycan synthesis with cell growth and division.

5H5G: Staphylococcus aureus FtsZ-GDP in T and R states

The tubulin-homolog protein FtsZ is essential for bacterial cell division. FtsZ polymerizes to form protofilaments that assemble into a ...

The Staphylococcus aureus cell division protein, DivIC, interacts ...

Many division proteins are highly conserved across bacterial species alluding to a common, basic mechanism. Central to division is a ...

The structural assembly switch of cell division protein FtsZ probed ...

FtsZ is a widely conserved tubulin-like GTPase that directs bacterial cell division and a new target for antibiotic discovery. This protein assembly machine ...

Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the ...

... assembly of specific cell division proteins (19, 20). Divisome ... division proteins, including the first and major cell division protein FtsZ (Fig.

The cell cycle of Staphylococcus aureus: An updated review - Barbuti

Another protein important in coordinating DNA replication with cell division is the recently discovered cell cycle regulator CcrZ (see Section 5.2 for more ...

Targeting the Achilles Heel of FtsZ: The Interdomain Cleft - Frontiers

The Z–ring is anchored to the membrane with the help of other essential cell division proteins, such as FtsA and ZipA of E. coli (Pichoff and Lutkenhaus, 2002).

Targeting Bacterial Cell Division: A Binding Site-Centered Approach ...

The constriction of the Z-ring splits the mother bacterial cell into two daughter cells of the same size. The Z-ring is formed by the polymerization of FtsZ, a ...