Strain and rate|dependent neuronal injury in a 3D in vitro ...

Strain and rate-dependent neuronal injury in a 3D in vitro ... - Nature

Using a 3D in vitro neuronal compression model, we investigated the role of impact strain and strain rate on neuronal lifetime, viability, and ...

Strain and rate-dependent neuronal injury in a 3D in vitro ... - PubMed

We find that strain magnitude and rate have profound, yet distinctively different effects on the injury pathology. While strain magnitude ...

Strain and Rate-Dependent Diffuse Axonal Injury of 3D Neuron ...

Using a 3D in vitro neuronal compression model, we investigated the role of impact strain and strain rate on neuronal lifetime, viability, and pathomorphology.

[PDF] Strain and rate-dependent neuronal injury in a 3D in vitro ...

Using a 3D in vitro neuronal compression model, the role of impact strain and strain rate on neuronal lifetime, viability, and pathomorphology is ...

(PDF) Strain and rate-dependent neuronal injury in a 3D in vitro ...

Using a 3D in vitro neuronal compression model, we investigated the role of impact strain and strain rate on neuronal lifetime, viability, and ...

Strain and rate-dependent neuronal injury in a 3D in vitro ... - Scite

Strain and rate-dependent neuronal injury in a 3D in vitro compression model of traumatic brain injury. Eyal Bar-Kochba. ,. Mark T. Scimone. ,. Jonathan B ...

Strain and rate-dependent neuronal injury in a 3D in vitro ... - OUCI

AbstractIn the United States over 1.7 million cases of traumatic brain injury are reported yearly, but predictive correlation of cellular injury to impact ...

High rate shear strain of three-dimensional neural cell cultures

Strain rate-dependent induction of reactive astrogliosis and cell ...

At 21 days in vitro (DIV) 3-D neuronal-astrocytic co-cultures were ... strain rate deformation and chemical hypoxia: an in vitro model for neural trauma.

High rate shear strain of three-dimensional neural cell cultures

Models that employ rapid mechanical deformation often exhibit a strain- and/or strain rate-dependent injury, thus substantiating the clinical observation that ...

trauma-induced-plasmalemma-disruptions-in-3-d-neural-cultures ...

Strain rate-dependent induction of reactive astrogliosis and cell death in three ... An in vitro model of traumatic neuronal injury: loading rate-dependent.

Strain and rate-dependent neuronal injury in a 3D in vitro ... - CoLab

Using a 3D in vitro neuronal compression model, we investigated the role of impact strain and strain rate on neuronal lifetime, viability, and pathomorphology.

Advancements in in vitro models of traumatic brain injury

One study considered repeated impacts to 3D neuronal cultures to show that neurite swelling is highly strain rate dependent in compression. Unlike for other ...

3D In-vitro TBI Models - Franck Lab

... strain and strain rate on neuronal survivability. Uniaxial Compression ... stress-strain relationship of neuronal injury in 3D in-vitro models.

Anin vitro traumatic injury model to examine the response of ...

Strain and rate-dependent neuronal injury in a 3D in vitro compression model of traumatic brain injury. Article Open access 02 August 2016. Mechanisms of cell ...

In Vitro Model for Traumatic Brain Injuries and Clinical Applications

... strain rate and acceleration can be used to predict the occurrence of brain injury. ... Strain and rate-dependent neuronal injury in a 3D in vitro.

A Precise, Controllable in vitro Model for Diffuse Axonal Injury ...

Strain and rate-dependent neuronal injury in a 3D in vitro compression model of traumatic brain injury. Sci. Rep. 6:30550. doi: 10.1038/srep30550. PubMed ...

A novel in vitro shear device for high strain rate injury of three ...

... strain rate injury of three-dimensional co-cultures of neurons and astrocytes ... 3-D cell cultures that undergo large shear deformations at high strain rates.

Brain strain rate response: addressing computational ambiguity and ...

Strain and rate-dependent neuronal injury in a 3D in vitro compression model of traumatic brain injury. Scientific Reports 2016;6:1–11 ...

High rate shear strain of three-dimensional neural cell cultures: A ...

Request PDF | High rate shear strain of three-dimensional neural cell cultures: A new in vitro traumatic brain injury model | The fidelity of cell culture ...