Strong Association of a Common Dihydropyrimidine ...

Strong association of a common dihydropyrimidine dehydrogenase ...

Our results show compelling evidence that, at least in distinct tumor types, a common DPYD polymorphism strongly contributes to the occurrence of ...

Strong Association of a Common Dihydropyrimidine ... - PLOS

Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience severe drug-adverse effects following ...

Strong Association of a Common Dihydropyrimidine ... - NCBI

Background. Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience severe drug- ...

Strong association of a common dihydropyrimidine dehydrogenase ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. by Eva Gross, ...

(PDF) Strong Association of a Common Dihydropyrimidine ...

Strong Association of a Common Dihydropyrimidine Dehydrogenase Gene Polymorphism with Fluoropyrimidine-Related Toxicity in Cancer Patients. PLOS ONE. 3 ...

Strong Association of a Common Dihydropyrimidine ... - CoLab

Background Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience severe drug-adverse effects ...

Strong Association of a Common Dihydropyrimidine ... - OUCI

Strong Association of a Common Dihydropyrimidine Dehydrogenase Gene Polymorphism with Fluoropyrimidine-Related Toxicity in Cancer Patients ... Authors: Eva Gross ...

PLOS ONE

Figure 1. Linkage disequilibrium (LD) structure based on 18 DPYD variants. Pairwise LD measures (r2) calculated with the software package Haploview [ref. 30] ...

Clinical Annotation for rs2297595 (DPYD); fluorouracil - PharmGKB

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PloS one. 2008 ...

Phenotypic Profiling of DPYD Variations Relevant to 5-Fluorouracil ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients . PLoS ONE. 2008.

Discovery of novel mutations in the dihydropyrimidine ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

DPYD*6 plays an important role in fluoropyrimidine toxicity ... - Nature

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

Rare Dihydropyrimidine Dehydrogenase Variants and Toxicity by ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS ONE. (2008) ...

Gastroesophageal Cancer + rs67376798 - PharmGKB

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PloS one. 2008 ...

Biomarkers of Fluorouracil Toxicity Insight From the PETACC-8 Trial

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients ...

Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR ...

... Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

Relationship between Single Nucleotide Polymorphisms and ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients . PLoS One. 2008.

High-resolution melting analysis of the common c.1905+1G>A ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients ...

ready for routine clinical application within personalized medicine?

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

Undetected Toxicity Risk in Pharmacogenetic Testing for ... - MDPI

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS ONE 2008, 3 ...