Strong association of a common dihydropyrimidine dehydrogenase ...

Our results show compelling evidence that, at least in distinct tumor types, a common DPYD polymorphism strongly contributes to the occurrence of ...

Strong Association of a Common Dihydropyrimidine ... - NCBI

Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience severe drug-adverse ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. by Eva Gross, ...

(PDF) Strong Association of a Common Dihydropyrimidine ...

PDF | Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience severe drug-adverse effects.

Relationship between Single Nucleotide Polymorphisms and ...

Furthermore, data on the association of DPYD ... Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related ...

Strong Association of a Common Dihydropyrimidine ... - CoLab

Background Cancer patients carrying mutations in the dihydropyrimidine dehydrogenase gene (DPYD) have a high risk to experience severe drug-adverse effects ...

Strong Association of a Common Dihydropyrimidine ... - OUCI

Strong Association of a Common Dihydropyrimidine Dehydrogenase Gene Polymorphism with Fluoropyrimidine-Related Toxicity in Cancer Patients ... Authors: Eva Gross ...

PLOS ONE

Figure 1. Linkage disequilibrium (LD) structure based on 18 DPYD variants. Pairwise LD measures (r2) calculated with the software package Haploview ...

Clinical Annotation for rs2297595 (DPYD); fluorouracil - PharmGKB

Please note alleles have been complemented to the plus chromosomal strand. From Publication. Strong association of a common dihydropyrimidine dehydrogenase gene ...

Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR ...

Gross E, Busse B, Riemenschneider M, Neubauer S, Seck K, Klein HG, Kiechle M, Lordick F, Meindl A (2008) Strong association of a common ...

Rare Dihydropyrimidine Dehydrogenase Variants and Toxicity by ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS ONE. (2008) ...

Fluorouracil Toxicity and DPYD - Medscape Reference

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

Phenotypic Profiling of DPYD Variations Relevant to 5-Fluorouracil ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients . PLoS ONE. 2008.

Discovery of novel mutations in the dihydropyrimidine ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

Dihydropyrimidine dehydrogenase pharmacogenetics for predicting ...

... Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients .

Undetected Toxicity Risk in Pharmacogenetic Testing for ... - MDPI

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS ONE 2008, 3 ...

High-resolution melting analysis of the common c.1905+1G>A ...

Strong association of a common dihydropyrimidine ... Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) ...

Dihydropyrimidine Dehydrogenase Gene Variation and Its ...

Side effects were classified according to CTCAE (common terminology criteria for adverse events V. 4) and the association between different polymorphisms and ...

ready for routine clinical application within personalized medicine?

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients.

Letter regarding Zhao et al. entitled “DPYD gene polymorphisms are ...

Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS One 2008; 3 ...