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Structural basis for the functional role of the Shu complex in ...


Structural basis for the functional role of the Shu complex ... - PubMed

The Shu complex, a conserved regulator consisting of Csm2, Psy3, Shu1 and Shu2 in budding yeast, plays an important role in the assembly of ...

Structural basis for the functional role of the Shu complex in ...

The Shu complex, a conserved regulator consisting of Csm2, Psy3, Shu1 and Shu2 in budding yeast, plays an important role in the assembly of the ...

[PDF] Structural basis for the functional role of the Shu complex in ...

The crystal structure of the yeast Shu complex is reported, revealing that Csm2, Psy3, Shu1 and Shu2 interact with each other in sequence to form a V-shape ...

Structural basis for the functional role of the Shu complex in ...

In budding yeast, Shu complex consists of Csm2, Psy3, Shu1, and Shu2, and plays important roles in both DNA damage repair and tolerance via the ...

(PDF) Structural basis for the functional role of the Shu complex in ...

However, the molecular basis for the assembly of the Shu complex and its functional role in DNA repair is still elusive. Here, we report the ...

Structural basis for the functional role of the Shu complex in ...

Structural basis for the functional role of the Shu complex in homologous recombination.NUCLEIC ACIDS RESEARCH,45(22). MLA, Zhang, Shicheng,et al."Structural ...

Structural basis for the functional role of the Shu complex in ...

Diffraction data. Wavelength (Å), 0.9785. Space group, P43212. Cell parameters. a, b, c (Å), 174.2, 174.2, 102.9. α, β, γ (°), 90, 90, 90.

Structural basis for the functional role of the Shu complex in ... - OUCI

Rong Lu; Tianlong Zhang; Jiangye Chen; Jianping Ding. List of references. Homologous recombination and its regulation, Nucleic Acids Res., № 40, с. 5795

The Shu complex is a conserved regulator of homologous ...

Here, we will describe canonical HR; however, the Shu complex primarily functions to promote HR in the context of DNA replication. During canonical HR, the DNA ...

Structural Analysis of Shu Proteins Reveals a DNA Binding Role ...

The yeast Shu complex, consisting of the proteins Shu1, Shu2, Psy3, and Csm2, maintains genomic stability by coupling post-replication repair to homologous ...

Shu complex | SGD

(2017) Structural basis for the functional role of the Shu complex in homologous recombination. Nucleic Acids Res 45(22):13068-13079 PMID: 29069504. SGD ...

Structural basis of homologous recombination

Zhang S et al (2017) Structural basis for the functional role of the Shu complex in homologous recombination. Nucleic Acids Res 45(22):13068 ...

Shu complex is an ATPase that regulates Rad51 filaments ... - bioRxiv

The gene products, Csm2, Psy3, Shu1 and Shu2, form the Shu complex heterotetramer(24, 25). Structural studies revealed that Csm2, Psy3 and Shu1 ...

human Shu complex functions with PDS5B and SPIDR to promote ...

Although the Shu complex is conserved in all eukaryotic lineages, including humans (14–17), both the precise function and composition of the ...

The human Shu complex promotes RAD51 activity by modulating ...

Hints to the human Shu complex function stemming from our work, and others, have shown that yeast Shu complex mutants are sensitive to the ...

Crystal structure of the Shu complex. (A) Overall ... - ResearchGate

... Structural basis for the functional role of the Shu complex in homologous recombination | The Shu complex, a conserved regulator consisting of Csm2, Psy3 ...

Structural Analysis of Shu Proteins Reveals a DNA Binding Role ...

Structural basis for the functional role of the Shu complex in homologous recombination · Shicheng ZhangLinlin Wang +5 authors. Jianping Ding. Biology. Nucleic ...

The Shu complex, which contains Rad51 paralogues, promotes ...

Although the Shu complex has been shown genetically to promote DNA repair through homologous recombination (HR), little is known about its ...

The Shu complex prevents mutagenesis and cytotoxicity of single ...

The yeast Shu complex, a conserved homologous recombination factor, aids in preventing replication-associated mutagenesis from DNA base damaging agents.

Distinct pathways of homologous recombination controlled by the ...

Structural basis for the functional role of the Shu complex in homologous recombination. Nucleic Acids Res. 45, 13068–13079 (2017). Article ...