Structure and decoy|mediated inhibition of the SOX18/Prox1|DNA ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Genetic disruption of Sox18 in a mouse model protects from tumour metastasis and established the SOX18 protein as a molecular target. Here, we ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

The transcription factor (TF) SOX18 drives lymphatic vessel development in both embryogenesis and tumour-induced neo-lymphangiogenesis.

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

The crystal structure of the SOX18 DNA binding high-mobility group (HMG) box bound to a DNA element regulating Prox1 transcription is reported, ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

PDF | The transcription factor (TF) SOX18 drives lymphatic vessel development in both embryogenesis and tumour-induced neo-lymphangiogenesis. Genetic.

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Klaus M, Prokoph N, Girbig M, Wang X, Huang YH, Srivastava Y, Hou L, Narasimhan ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.Nucleic Acids Research. First author. Miriam Klaus, Nina Prokoph ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction ... Authors: Miriam Klaus; Nina Prokoph; Mathias Girbig; Xuecong Wang; Yong-Heng Huang ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Four decoys potently inhibited DNA binding of SOX18 in vitro and did not interact with non-SOX TFs. Serum stability, nuclease resistance and ...

Structure and decoy-mediated inhibition of the SOX18 ... - Altmetric

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Published in. Nucleic Acids Research, March 2016. DOI, 10.1093/nar/gkw130. Pubmed ID.

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

... Nucleic Acids Research, volume 44, issue 8, pages 3922-3935. Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Miriam Klaus. ,. Nina ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Miriam Klaus, Nina Prokoph, Mathias Girbig, Xuecong Wang, Yong Heng Huang, Yogesh ...

4y60 - Structure of SOX18-HMG/PROX1-DNA - Summary

Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Nucleic Acids Res., 44:3922-3935, 2016. Cited by 42. PubMed: 26939885 · DOI: 10.1093 ...

Small-Molecule Inhibitors of the SOX18 Transcription Factor

28. Klaus, M. ∙ Prokoph, N. ∙ Girbig, M. ... Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Nucleic Acids Res. 2016; 44:3922 ...

Article Small-Molecule Inhibitors of the SOX18 Transcription Factor

The stable binding pose for Sm4 in the SOX18/DNA structure puts the inhibitor ... Francois, et al. Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Modified SOX decoys potently inhibit DNA binding of SOX18. The ...

The left panel shows a scheme of the decoys and a structural cartoon of the termini to illustrate the modifications. (A) Unmodified decoy 'NAT', (B) 'PS' decoy ...

Small-Molecule Inhibitors of the SOX18 Transcription Factor

(C) Docking of the SOX18/DNA structure into the structure of the Notch transcription complex. ... Structure and · decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Functional domain analysis of SOX18 transcription factor using a ...

Docking the SOX18/DNA structure into the structure of this Notch ... Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.

Role of the SOX18 protein in neoplastic processes (Review)

Protein structure and DNA-binding of SOX18. ... Image from the RCSB PDB of 4Y60: Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA ...

Homodimerization regulates an endothelial specific signature of the ...

et al. Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction . Nucleic Acids Res. 2016. ;. 44. : 3922. –. 3935 . Google ...

Oncogenic Herpesvirus Engages Endothelial Transcription Factors ...

Genetic depletion or chemical inhibition of SOX18 caused a decrease of KSHV genome copy numbers. PROX1 interacted with ORF50, the viral initiator of lytic ...