Study Shows Promise of New Anti|KRAS Drug for Pancreatic Cancer

Study Shows Promise of New Anti-KRAS Drug for Pancreatic Cancer

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS successfully shrunk tumors or stopped ...

Study shows promise of new anti-KRAS drug for pancreatic cancer

A small molecule inhibitor that attacks the difficult cancer-causing gene mutation KRAS successfully shrunk tumors or stopped cancer growth ...

Chemo Boosts KRAS Inhibitor Against Pancreatic Cancer - NCI

Two new studies in mice show that adding chemotherapy to an experimental KRAS inhibitor called MRTX1133 greatly reduced tumor growth and spread compared with ...

MSK Discovery Suggests Opportunity to Improve Effectiveness of ...

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial ...

Vaccine Targeting KRAS in Pancreatic and Colorectal Cancer ...

A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients with pancreatic or colorectal cancer.

Study shows promise of new anti-KRAS drug for pancreatic cancer

A small molecule inhibitor that attacks the difficult to target, cancer-causing gene mutation KRAS, found in nearly 30 percent of all human ...

Study Shows Success of New Anti-KRAS Drug for Pancreatic Cancer

Researchers show how new anti-KRAS drug for pancreatic cancer shrinks tumors and interacts with the immune system.

Progress and Promise—Research in 2023

The emergence of drugs that can inhibit KRAS, the driver of 90 percent of all pancreatic cancers, gave hope for a new era of pancreatic cancer ...

Discovery suggests opportunity to improve effectiveness of KRAS ...

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise ...

New cancer drug shows promise in pancreatic tumors

A new, chemically modified cancer drug shows promising effects against pancreatic tumors, according to a study published recently in eLife.

Experimental Therapy Shows Promise in Pancreatic Cancer Clinical ...

The mouse studies found evidence that tumors had been flooded by natural killer immune cells, a sign that the drug had accomplished its goal of ...

Hope on the Horizon: A Revolution in KRAS Inhibition Is Creating a ...

Hope on the Horizon: A Revolution in KRAS Inhibition Is Creating a New Treatment Paradigm for Patients with Pancreatic Cancer · Abstract · The ...

New Research Suggests How to Improve Effectiveness of KRAS ...

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial ...

Targeting a KRAS Variant in Advanced Pancreatic Cancer

Scientists are testing a new targeted protein degradation (TPD) approach for solid tumors, as a way to eliminate KRAS G12D and block its ability to send ...

KRAS Inhibitors in Pancreatic Cancer: Hope on the Horizon?

Only about 1%-2% of tumors have the specific KRAS G12C mutation that these drugs target. These KRAS inhibitors have shown limited efficacy in ...

Targeting KRAS for the potential treatment of pancreatic ductal ...

Recent therapeutic approaches for KRAS-driven tumors focus on mutation-specific drugs such as selective KRAS G12C inhibitors and son of sevenless 1 pan-KRAS ...

Novel drug combination shows promise in treating pancreatic cancer

The study was the first to confirm that human pancreatic cells treated with the KRAS ...

An mRNA vaccine to treat pancreatic cancer

... anti-tumor immune response in half the participants in a small study ... Experimental mRNA HIV Vaccine Shows Promise in Animals ...

Study defines mechanisms underlying promising precision therapy ...

Most pancreatic cancers harbor mutations in the KRAS gene, which drives many of the features that make this disease so lethal. New precision ...

Massey researcher's drug shows promise as a possible treatment for ...

“We demonstrated FGTI-2734's therapeutic efficacy in clinical samples from 12 pancreatic cancer patients with mutant KRAS tumors,” Sebti said. “ ...