Study reveals how cancer immunotherapy may cause heart ...

Myocarditis is driven by a different immune response than the anti-tumor one, suggesting that the serious complication could one day be ...

Study Reveals How Cancer Immunotherapy Leads to Deadly Form ...

The team identified specific changes to the heart and pinpointed factors in the blood that may indicate whether a patient's myocarditis is ...

How Cancer Immunotherapy Fuels Heart Inflammation in Some ...

New research shows that immune cells and connective-tissue cells in the heart muscle appear to be driving the immune response that triggers the ...

How cancer immunotherapy may cause heart inflammation in some ...

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart ...

Study Reveals How Cancer Immunotherapy Leads to Deadly Form ...

The researchers found that damage to the heart is driven by a different immune ... could one day be managed without halting cancer therapy.

Science Reveals Why Cancer Immunotherapies Can Sometimes ...

Specific types of immune cells unleashed by cancer immunotherapy appear to cause myocarditis, an inflammatory condition that can weaken the ...

What Causes Immunotherapy's Heart-Related Side Effects? - NCI

Researchers have found a potential cause of myocarditis caused by immune checkpoint inhibitor treatment: T cells attacking a protein in ...

Cardiac Toxicity Associated with Cancer Immunotherapy and ... - NCBI

PD/PDL-1 inhibitors can cause myocarditis, rare but potentially fulminant and associated with a high fatality rate. CAR-T therapy is associated ...

Q&A: How a partnership between physicians and researchers aims ...

Study reveals how cancer immunotherapy may cause heart inflammation in some patients. In the mid-2010s, oncologist Kerry Reynolds and ...

Broad Institute | A new study reveals the roots of dangerous heart ...

A new study reveals the roots of dangerous heart inflammation that occurs in some patients taking cancer immunotherapy drugs and suggests it ...

Heart Health: Mitigating Collateral Damage From Immunotherapy

Approximately 1% of cancer patients receiving ICI therapy develop myocarditis, which can cause pain, irregular heart rhythms, and sometimes heart failure.

Cancer patients receiving immunotherapy drugs have a higher risk ...

A study of over a thousand cancer patients treated with immunotherapy drugs has found these patients are at greater risk of heart problems, ...

Study confirms some cancer immunotherapies may lead to ...

Immune checkpoint inhibitors (ICIs) have transformed cancer care by unleashing T-cells to fight tumors, but they can cause serious ...

Cancer immunotherapy drugs linked with more serious heart effects

Vanderbilt University Medical Center investigators have identified a growing number of serious and sometimes fatal cases of heart problems ...

Cancer immunotherapy can cause heart muscle damage

Autoimmune reactions are in fact among the most common causes of myocarditis. And such reactions can be triggered by cancer immunotherapies due ...

Immunotherapy-associated cardiovascular toxicities: insights from ...

Immune checkpoint inhibitors (ICIs) have become a widely accepted and effective treatment for various types of solid tumors. Recent studies ...

Investigating the Side Effects of Cancer Immunotherapy - NCI

Their results were consistent with findings in mice showing that the use of an immunotherapy drug to boost the immune response can increase the ...

Cardiotoxicity risk factors with immune checkpoint inhibitors

In our study we found that patients treated with pembrolizumab have higher incidence of cardiac events. In addition, female gender, African ...

Myocarditis occurrence with cancer immunotherapy across ... - Nature

Antibodies targeting the PD-1, PD-L1, and CTLA-4 immune checkpoint axis have been used in a variety of tumor types. They achieve anti-tumor ...

Immunotherapy Side Effects | Cancer Research Institute

While chemotherapy and radiation target both cancerous and healthy cells, immunotherapy works by stimulating the immune system to attack cancer cells. This ...