Study sheds light on crucial DNA binding protein

Study sheds light on crucial DNA binding protein - VUMC News

Researchers at Vanderbilt University have established the molecular basis for the function of Replication Protein A (RPA), a DNA binding ...

Biochemical and Structural Analyses Shed Light on the Mechanisms ...

The above data verified that the ZFD and CTD of RadD were important binding sites for branched DNA. RD1 and RD2 did not bind to DNA, but their ...

Neutrons help shed light on critical protein activity that protects our ...

As the primary single-stranded DNA binding protein in humans, RPA is absolutely essential to virtually all processes that maintain and propagate ...

Flexible structural arrangement and DNA-binding properties of ...

The genome-organizing protein p6 of Bacillus subtilis bacteriophage φ29 plays an essential role in viral development by activating the ...

Walter Chazin | Vanderbilt University

... sheds light on how DNA replication is initiated in humans. Read More. Mar ... Study sheds light on crucial DNA binding protein. Researchers at Vanderbilt ...

New insight into the protein mutations that cause Rett syndrome

Yet scientists understand little about how this essential protein does its crucial work at the molecular level. “People have been studying this ...

A DNA-binding protein capture technology that purifies proteins by ...

DNA-protein interactions play an essential role in many biological processes, such as gene expression regulation, genome maintenance, DNA repair, DNA ...

Breaking the Protein-DNA Bond | News | Northwestern Engineering

Study finds that free-floating proteins break up protein-DNA bonds at the single-binding site ... The verdict is in: too many single, flirty ...

A vital game of hide-and-seek elucidated by novel single-molecule ...

... cell. New research sheds light on the mechanisms with which DNA-binding proteins search the genome for their specific binding sites.

Unlocking the secrets of DNA-binding proteins in nuclear extracts ...

In a newly published exciting paper from the research group of Bennett Van Houten they reveal a revolutionary new method for directly measuring and analyzing ...

Study sheds light on DNA sculpting properties of enigmatic protein

Although the extent of what XPG does in human cells is still only partially understood, scientists have long known that the protein is essential ...

Research into RNA-DNA 'R-loops' could shed light on cancer ...

Proteins such as AQR are known as helicases, and play a crucial role in DNA replication and repair within cells. ... Xue has already learned that ...

New Study Affirms the Role of Specialized Protein in Assuring ...

NYU Langone-led research demonstrates DNA-binding protein CTCF essential for precise expression of genes controlling plan of developing ...

Critical importance of DNA binding for CSL protein functions in ...

DNA-binding activities of CSL proteins are required for their antagonism in cell adhesion. (A) Both Δcbf11 and cbf11DBM–TAP cells display higher adhesion to ...

The Solution Structure of an AlcR-DNA Complex Sheds Light onto ...

In addition, the involvement of the N-terminal residues upstream of the AlcR zinc cluster in DNA binding is clearly highlighted, and the pivotal role of R6 is ...

Predicting Target DNA Sequences of DNA-Binding Proteins ... - PLOS

Based on the analyses conducted in this study, the conformational change of proteins upon binding DNA was shown to be the key factor. This study sheds light on ...

AI Sheds New Light on the 'Code of Life' - USC Dornsife

“We want to predict binding preferences of gene regulatory proteins, called transcription factors, to DNA with chemically modified nucleotides ...

UMD Researchers Study the Intricate Processes Underpinning ...

Notably, transcription factors (TFs)—proteins that bind specific DNA sequences within the chromatin polymer and turn genes on or off—exhibit ...

Intercellular Mechanisms Regulate Gene Expression in Cancer Cells

Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during ...

New study 'sheds light' on the mechanisms safeguarding the genome

... DNA damaging UV radiation ... Delving further into these mechanisms the researchers found that HUR, an RNA binding protein ...