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- Iron is a specific cofactor for distinct oxidation| and aggregation ...🔍
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- In vitro and in vivo degradation of Aβ peptide by peptidases coupled ...🔍
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Suppression of Aβ toxicity by puromycin|sensitive aminopeptidase is ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
The accumulation of β-amyloid (Aβ) peptide in the brain is one of the pathological hallmarks of Alzheimer's disease and is thought to be of ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
PSA is a potent suppressor of Aβ toxicity and reduces brain Aβ levels in flies. PSA is cytoplasmic but there is no direct epistatic interaction with Aβ in vivo.
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. Antonina J. Kruppa a,b,c, Stanislav Ott c, Dhia ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. by Antonina J Kruppa, Stanislav Ott, ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
27 puromycin-sensitive aminopeptidase (PSA) as a potent suppressor of Aβ toxicity in a Drosophila model system. 28. We established that coexpression of ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity · Antonina J. Kruppa · Stanislav Ott · Dhia S.
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is ...
Background: Sarcoidosis is a multisystem granulomatous disease of unknown aetiology. Proteins present within the alveolar space early in sarcoidosis disease may ...
Figure 4 from Puromycin-sensitive aminopeptidase (PSA/NPEPPS ...
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity · Biology, Medicine. Biochimica et Biophysica Acta.
Metabolic changes may precede proteostatic dysfunction in a ... - NCBI
UAS-Aβ stocks were crossed with flies ... Suppression of Abeta toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.
Results & submissions : REF 2014 : Output details
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. Type. D - Journal article.
Iron is a specific cofactor for distinct oxidation- and aggregation ...
Aβ and iron exhibit distinct toxicity. ... Suppression of Abeta toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.
Puromycin-sensitive amino peptidase also known as cytosol alanyl aminopeptidase or alanine aminopeptidase (AAP) (EC 3.4.11.14) is an enzyme that in humans ...
Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes ...
Puromycin-sensitive aminopeptidase (PSA/NPEPPS) is a novel modifier of TAU-induced neurodegeneration with neuroprotective effects via direct proteolysis of TAU ...
In vitro and in vivo degradation of Aβ peptide by peptidases coupled ...
μg of purified recombinant human puromycin sensitive aminopeptidase [43] and a source of NEP in 200 ... toxicity by modulating Aβ-degrading enzymes in HT22 cells.
Mutation of active site residues of the puromycin-sensitive ... - OUCI
Publications that cite this publication · Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.
Aminopeptidase A contributes to biochemical, anatomical and ...
The cyclisation of the glutamate in position 3 requires prior removal of the Aβ N-terminal aspartyl residue to allow subsequent ...
Elena Speretta - Google Scholar
2010. Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. AJ Kruppa, S Ott, DS Chandraratna, JA ...
The Amyloid-β Pathway in Alzheimer's Disease | Molecular Psychiatry
... Aβ toxicity via a feedback loop [228, 229]. Critical insights derive ... A sensitive aβ oligomer assay discriminates Alzheimer's and aged control ...
Stanislav Ott - Google Scholar
2014. Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. AJ Kruppa, S Ott, DS Chandraratna, JA ...
Puromycin‐sensitive aminopeptidase is the major peptidase ...
To identify these key peptidases, we investigated the degradation in cell extracts of model Q‐rich fluorescent substrates and peptides containing 10–30 Q's.