T cell response to SARS|CoV|2 infection in humans

T cell response to SARS-CoV-2 infection in humans - PubMed Central

Understanding the T cell response to SARS-CoV-2 is critical to vaccine development, epidemiological surveillance and disease control strategies.

The T cell immune response against SARS-CoV-2 - Nature

Despite the considerable mortality rate of primary SARS-CoV-2 infection, most people do survive and eradicate the virus. SARS-CoV-2-specific T ...

T cell response to SARS-CoV-2 infection in humans - PubMed

A complex pattern of T cell response to SARS-CoV-2 infection has been demonstrated, but inferences regarding population level immunity are ...

T Cell Responses to SARS-CoV-2 - Annual Reviews

A large body of evidence generated in the last two and a half years addresses the roles of T cells in SARS-CoV-2 infection and following vaccination.

Profiling the SARS-CoV-2-specific T-cell response - The Lancet

Because MERS-CoV does not cause infections in Europe, this ... Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

T cell immunity to SARS-CoV-2 - ScienceDirect.com

Collectively, the current human data indicate that early induction of functional SARS-CoV-2-specific T cells correlate with viral control and mild disease, ...

Current understanding of T cell immunity against SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, also called 2019-nCoV previously) is the pathogen of human coronavirus disease 2019 ...

Post-pandemic memory T cell response to SARS-CoV-2 is durable ...

Although it has been demonstrated that spike T cell responses generated upon natural infection and vaccination against the ancestral SARS-CoV-2 ...

Understanding T cell responses to COVID-19 is essential ... - Science

Durable T cell responses to SARS-CoV-2 antigens after infection or vaccination improve immune-mediated viral clearance. To date, population-based surveys of ...

T Cell Response to SARS-CoV-2 Coinfection and Comorbidities

Adaptive immune cells, especially T cells, have been extensively investigated in regard to SARS-CoV-2 infection. However, human health and T ...

T cell response to SARS-CoV-2 infection in humans - PLOS

A complex pattern of T cell response to SARS-CoV-2 infection has been demonstrated, but inferences regarding population level immunity are hampered by ...

Long COVID manifests with T cell dysregulation, inflammation and ...

Long COVID (LC) occurs after at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, yet its etiology ...

T cell response to intact SARS-CoV-2 includes coronavirus cross ...

Resultant CD8 T cells recognize SARS-CoV-2–infected respiratory tract cells, and CD4 T cells detect inactivated whole viral antigen.

SARS-CoV-2 breakthrough infections enhance T cell response ...

These variant-specific T cell responses accounted for 9%–15% of the total epitope repertoire. Overall, BTIs boost vaccine-induced immune responses by increasing ...

T-cell response to SARS-CoV-2: kinetic and quantitative aspects ...

Such distinction is still not established in human coronavirus infections but data in animal models support the role of T cells in viral ...

SARS-CoV-2-specific antibody and T-cell responses 1 year after ...

SARS-CoV-2-specific antibody and T-cell responses 1 year after infection in people recovered from COVID-19: a longitudinal cohort study

Article Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...

In sum, the ability to measure and understand the human CD4+ and CD8+ T cell responses to SARS-CoV-2 infection is a major knowledge gap ...

What is the role of T cells in COVID-19 infection? Why immunity is ...

Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals. Cell 2020; 181(7): 1489-501.e15 ...

T-cell immunity to SARS-CoV-2: what if the known best is ... - Frontiers

Hence, SARS-CoV-2-infected mice expressing human angiotensin-converting enzyme 2 (ACE2) induced strong polyfunctional CD4+ and CD8+ T cell responses that could ...

Mapping and role of T cell response in SARS-CoV-2–infected mice

Here, using mice sensitized for infection with SARS-CoV-2 by transduction with an adenovirus expressing the human receptor (Ad5-hACE2), we ...