TRP channels
TRP (transient receptor potential) ion channel family - Nature
TRP channels are responsible for various sensory responses including heat, cold, pain, stress, vision and taste and can be activated by a number of stimuli.
Transient receptor potential channel - Wikipedia
Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types.
Transient Receptor Potential (TRP) Channels - PMC - PubMed Central
Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists ...
Transient Receptor Potential channels (TRP) | Introduction
TRP channels may be generally described as cation permeable channels that function as cellular sensors responding to a broad range of stimuli. Transient ...
Advances in TRP channel drug discovery: from target validation to ...
In this Review, we discuss recent findings in TRP channel structural biology that can affect both drug development and clinical indications.
Transient Receptor Potential Channel - ScienceDirect.com
TRP channels may be generally described as cation channels that increase intracellular Ca2+ levels. They are activated by diverse stimuli such as changes in ...
TRP channels act as molecular sensors of multiple stimuli, ranging from changes in pH, chemical agents, temperature, and osmolarity.
Transient Receptor Potential channels (TRP) | Ion channels
TRP subunits contain six putative TM domains and assemble as homo- or hetero-tetramers to form cation selective channels with diverse modes of activation.
TRP channels: An overview - ScienceDirect.com
TRP channels are multifunctional sensors of environmental cues in the form of physical and chemical stimuli. They are widely expressed in the CNS and peripheral ...
The transient receptor potential family of ion channels
Most TRP channels are localized in the plasma membrane, where they have an essential role in the influx and/or transcellular machinery that ...
TRP channels - Reactome Pathway Database
Reactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge.
Transient receptor potential channels: current perspectives on ...
TRP channels are gated by a wide variety of mechanisms and stimuli (including thermal, mechanical and chemical), and function in a plethora of ...
Abstract The TRP (Transient Receptor Potential) superfamily of cation channels is remarkable in that it displays greater diversity in ...
TRP channels in health and disease at a glance
TRPs are the cellular safeguards that sense various cell stresses and environmental stimuli and translate this information into responses at the organismal ...
Targeting TRP channels: recent advances in structure, ligand ...
In this short review, we summarize recent progresses toward understanding the structural basis of TRP channel function, as well as potential ligand binding ...
TRP channels: Role in neurodegenerative diseases and therapeutic ...
This review articulates TRP channels' physiological and pathological role in exploring new therapeutic interventions in neurodegenerative diseases.
Function of TRP channels in monocytes/macrophages - Frontiers
Here, we summarize recent findings on the expression and function of TRP channels in macrophages and discuss their role as modulators of macrophage activation ...
TRP Channels: Methods and Protocols | SpringerLink
This book aims to provide a guide to researchers on how to work with Transient Receptor Potential (TRP) channels, describing current methodologies and ...
A thermodynamic framework for understanding temperature sensing ...
The exceptionally high temperature sensitivity of certain transient receptor potential (TRP) family ion channels is the molecular basis of hot and cold ...
TRP Channels and Pain - Annual Reviews
three members of the transient receptor potential (TRP) ion channel family—TRPV1, TRPM8, and TRPA1—as molecular detectors of thermal and ...