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- Target|decoy false discovery rate estimation using Crema🔍
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Target|small decoy search strategy for false discovery rate estimation
Target-small decoy search strategy for false discovery rate estimation
One of the most important steps in peptide identification is to estimate the false discovery rate (FDR). The most commonly used method for ...
Target-small decoy search strategy for false discovery rate estimation
Target-small decoy search strategy for false discovery rate estimation. BMC Bioinformatics. 2019 Aug 23;20(1):438. doi: 10.1186/s12859-019-3034-8.
Target-small decoy search strategy for false discovery rate estimation
One of the most important steps in peptide identification is to estimate the false discovery rate (FDR). The most commonly used method for estimating FDR is ...
Target-decoy false discovery rate estimation using Crema - bioRxiv
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution.
A theoretical foundation of the target-decoy search strategy for false ...
Target-decoy search (TDS) is currently the most popular strategy for estimating and controlling the false discovery rate (FDR) of peptide identifications.
Target-Decoy Search Strategy for Mass Spectrometry-Based ...
... incorrect identifications. Keywords: Proteomics, Target-decoy, False positive, False discovery, Mass spectrometry, Estimation. 1. Introduction. Peptide and ...
Target-small decoy search strategy for false discovery rate estimation
The most commonly used method for estimating FDR is the target-decoy search strategy (TDS). While this method is simple and effective, it is ...
Mascot help: Automatic target-decoy searching and ... - Matrix Science
If you select a target FDR, an appropriate score threshold is set based on the estimated FDR, but no peptide matches from the target database are added, ...
False Discovery Rate (FDR) Tutorial | Protein Identification
Therefore the number of decoy hits cannot be used to estimate the number of false target hits anymore. Mistake 2. Use target-decoy to validate a search ...
Target–decoy false discovery rate estimation using Crema - OSTI.GOV
Crema is compatible with a variety of existing database search tools and provides a straightforward way to obtain robust FDR estimates. Read ...
A theoretical foundation of the target-decoy search strategy for false ...
Motivation: Target-decoy search (TDS) is currently the most popu- lar strategy for estimating and controlling the false discovery rate. (FDR) of peptide ...
Target-Decoy Approach and False Discovery Rate - Semantic Scholar
It is argued that TDA is not needed when accurate p-values of individual Peptide-Spectrum Matches are available and that it is easy to develop a non-TDA ...
Decoy-free protein-level false discovery rate estimation
The mainstream approach for FDR estimation is the target-decoy strategy, which searches ... rate that discoveries are false' is small. In contrast, pFDR ...
False Discovery Rate Estimation in Proteomics - BIOCEV
There are many different strategies to estimate FDR like the nonparametric simple target-decoy (TD) database searches [4, 6] and parametric or semi-parametric ...
2021-12-07. Here we describe how you can estimate the false discovery rate (FDR) when matching your spectra against a FASTA sequence database using spectra ...
Target-Decoy Approach and False Discovery Rate
A Pipeline for Peptide Detection Using Multiple Decoys. Chapter © 2023. Target-small decoy search strategy for false discovery rate estimation.
algorithm for decoy-free false discovery rate estimation in XL-MS/MS ...
Theoretically, FDR estimates can be >1, and likewise, the strategy of competing target with decoy peptides for the available experimental ...
A Scalable Approach for Protein False Discovery Rate Estimation in ...
Owing to its conceptual and practical simplicity, the most widely used strategy to estimate FDR in proteomics is the target–decoy database search strategy ( ...
Averaging Strategy To Reduce Variability in Target-Decoy Estimates ...
Decoy database search with target-decoy competition (TDC) provides an intuitive, easy-to-implement method for estimating the false discovery ...
Target-small decoy search strategy for false discovery rate estimation
Elias JE, Gygi SP. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat Methods. 2007;4(3):207 ...