Targeting the Molecular and Immunologic Features of ...

Targeting the Molecular and Immunologic Features of ... - PubMed

Leiomyosarcoma (LMS) is a rare, aggressive mesenchymal tumor with smooth muscle differentiation. LMS is one of the most common histologic ...

Targeting the Molecular and Immunologic Features of ... - MDPI

Leiomyosarcoma (LMS) is a rare, aggressive mesenchymal tumor with smooth muscle differentiation. LMS is one of the most common histologic subtypes of soft ...

Targeting the Molecular and Immunologic Features of ...

The LMS immune microenvironment is highly infiltrated with tumor-associated macrophages and tumor-infiltrating lymphocytes, which may represent promising ...

(PDF) Targeting the Molecular and Immunologic Features of ...

LMS often demonstrates aggressive tumor biology, with a higher risk of developing distant metastatic disease than most sarcoma histologic types.

Targeting the Molecular and Immunologic Features of ... - CoLab

LMS is one of the most common histologic subtypes of soft tissue sarcoma; it most frequently occurs in the extremities, retroperitoneum, or uterus. LMS often ...

Targeting the Molecular and Immunologic Features of ... - OUCI

LMS is one of the most common histologic subtypes of soft tissue sarcoma; it most frequently occurs in the extremities, retroperitoneum, or uterus. LMS often ...

Cancers | Free Full-Text | Targeting the Molecular and Immunologic ...

Article Versions Notes ; article xml uploaded. 31 March 2023 10:01 CEST, Update, - ; article pdf uploaded. 31 March 2023 10:01 CEST, Version of Record, - ...

Targeting the molecular and cellular interactions of the bone marrow ...

Targeting the molecular and cellular interactions of the bone marrow niche in immunologic disease ... Curr Allergy Asthma Rep. 2014 Feb;14(2):402. doi: 10.1007/ ...

Targeting the Molecular and Immunologic Features of ... - EBSCOhost

Document Type: Article ; Subject Terms: *LEIOMYOSARCOMA *IMMUNE checkpoint inhibitors *MOLECULAR pathology *MACROPHAGES *SOFT tissue tumors *TUMOR markers *DNA ...

Molecular and immunological features of TREM1 and its emergence ...

Immune checkpoint inhibitors (ICIs) and monoclonal antibodies (mAbs) targeting inhibitory receptors have been subjected to clinical trials, and striking success ...

Genetic and immunologic features of recurrent stage I lung ... - Nature

... targets. This study investigates the molecular and immunologic features of early recurrence in stage I lung adenocarcinoma using a large ...

HER2+ endometrioid endometrial cancer possesses distinct ...

HER2+ endometrioid endometrial cancer possesses distinct molecular and immunologic features associated with a more active immune microenvironment and worse ...

Genomic, Pathway Network, and Immunologic Features ... - Cell Press

... immune escape of these tumors and limited response rates to immune checkpoint therapies. Small molecules, antibodies, or miRNA mimetics targeting these ...

Targeted Therapy for Cancer - NCI

Targeted therapy is a type of cancer treatment that targets the changes in cancer cells that help them grow, divide, and spread.

Molecular and modular intricacies of precision oncology - Frontiers

Gene and molecular-targeted therapy (designed to target only cancer cells) and Immunotherapy (used to boost body's immune system against cancer), are the major ...

LAG-3: from molecular functions to clinical applications

In addition to PD-1 and CTLA-4, a variety of stimulatory and inhibitory coreceptors are involved in the regulation of T cell activation. Such coreceptors are ...

Targeting metabolic pathways to counter cancer immunotherapy ...

Research shows that metabolic modulation of the tumor microenvironment can enhance antitumor immunity. Here, we discuss recent preclinical and ...

Advancements in clinical aspects of targeted therapy and ...

However, recent advances in molecular biology and immunology enable to develop highly targeted therapies for many forms of breast cancer. The ...

Molecular Subtypes Based on Immunologic and Epithelial ...

Most glioma treatments with notable survival benefits, such as radiation and chemotherapy, rely on nonspecific targeting of proliferating cells ...

Immunological mechanisms and therapeutic targets of fatty liver ...

Intestinal microbes influence the immune response in the liver through pathogen-associated molecular patterns (PAMPs), and PAMPs further mediate ...