Targeting the Tumor Immune Microenvironment for Biomarker and ...

Dr. Valerie Chew from Duke-National University of Singapore (NUS) Medical School presents on biomarkers and therapies for Hepatocellular ...

Advantages of targeting the tumor immune microenvironment over ...

Lessons learned from immune checkpoint-targeting cancer therapy. Drugs that target ICPs, including but not limited to anti-CTLA-4 and anti-PD-1/ ...

Targeting of the tumor immune microenvironment by metformin - PMC

Stimulating antitumor immunity is an attractive idea for suppressing tumors. CD4 + and CD8 + T cells as well as natural killer cells (NK) are the primary ...

The components of tumor microenvironment as biomarker for ... - NCBI

Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy. Signal Transduct Target ...

Therapeutic targets and biomarkers of tumor immunotherapy - Nature

Cancers are highly complex diseases that are characterized by not only the overgrowth of malignant cells but also an altered immune response ...

Targeting the tumor microenvironment: Potential strategy for cancer ...

Cellular and stromal components including tumor cells, immune cells, mesenchymal cells, cancer-linked fibroblasts, and extracellular matrix, constituent tumor ...

Targeting the immune microenvironment for ovarian cancer therapy

This review aims to provide an overview of the OC TME and explore its potential as a therapeutic strategy.

Targets of tumor microenvironment for potential drug development

For instance, immune cells in the TME can inhibit the efficacy of immunotherapy and reduce patients' response to ICIs, and the TME can limit the ...

IA13 Targeting Myeloid Cells that Define the Tumor Immune ...

The composition of the tumor immune microenvironment dictates responsiveness to cancer immunotherapies, though discrete biomarkers to predict responsiveness ...

Targeting the tumor microenvironment: removing obstruction to ...

The balance between a large number of different immune cells, immune factors, and signaling molecules determines the outcome of the antitumor immune response.

Therapeutic Targeting of the Tumor Microenvironment

The TME is populated by numerous diverse cell types including heterogeneous cancer cells; immune cells, for example T and B lymphocytes, TAMs, ...

Targeting the tumor microenvironment: removing obstruction to ...

Early infiltration of tumors by immune cells such as macrophages, lymphocytes, natural killer (NK) cells, and dendritic cells (DCs) is crucial for tumor control ...

Immunotherapy: Reshape the Tumor Immune Microenvironment

DCs are specialized antigen-presenting cells that are key targets for cancer vaccines because of their unique ability to link innate and adaptive immunity (198) ...

Exploring and Targeting the Tumor Immune Microenvironment of ...

tumor immune microenvironment and immunotherapy in head and ...

... cancer treatment that leverages the immune system for targeting and destroying cancer cells. ... tumor microenvironment (TME) in HNSCC play ...

Targeting Tumor Microenvironment for Cancer Therapy - MDPI

The interplay between cancer cells and neighboring cells, including stromal and immune system cells (which frequently appear due to inflammation at the tumor ...

Tumour immune microenvironment biomarkers predicting cytotoxic ...

Prospective trials using standardised validated markers, such as the Immunoscore, are required to rationalise the use of adjuvant chemotherapy and target ...

Infiltrating treg reprogramming in the tumor immune ...

Biomarker Research volume 12, Article number: 97 ... targeting the immune cell regulatory pathway in tumor immune microenvironment (TIME).

Targeting the Tumor Immune Microenvironment - Creative Biolabs

The tumor immune microenvironment (TIME) comprises all immune components of tumors including immune cells, extracellular immune factors and cell surface ...

Reshaping the systemic tumor immune environment (STIE) and ...

The stromal and immune landscape of nasopharyngeal carcinoma and its implications for precision medicine targeting the tumor microenvironment.