Targets of T Cell Responses to SARS|CoV|2 Coronavirus in ...

Targets of T Cell Responses to SARS-CoV-2 Coronavirus ... - PubMed

We detected SARS-CoV-2-reactive CD4 + T cells in ∼40%-60% of unexposed individuals, suggesting cross-reactive T cell recognition between circulating "common ...

Article Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...

We detected SARS-CoV-2-reactive CD4 + T cells in ∼40%–60% of unexposed individuals, suggesting cross-reactive T cell recognition between circulating “common ...

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...

CD4+ T cell responses to spike, the main target of most vaccine efforts, were robust and correlated with the magnitude of the anti-SARS-CoV-2 ...

T Cell Responses to SARS-CoV-2 - Annual Reviews

A large body of evidence generated in the last two and a half years addresses the roles of T cells in SARS-CoV-2 infection and following vaccination.

The T cell immune response against SARS-CoV-2 - Nature

The magnitude of the SARS-CoV-2-specific CD4+ and CD8+ memory T cell response is typically around 0.5% and 0.2% of the repertoire, respectively, ...

T cell response to SARS-CoV-2 infection in humans - PubMed Central

Symptomatic adult COVID-19 cases consistently show peripheral T cell lymphopenia, which positively correlates with increased disease severity, duration of RNA ...

T-cell response to SARS-CoV-2: kinetic and quantitative aspects ...

Such distinction is still not established in human coronavirus infections but data in animal models support the role of T cells in viral ...

T cell response to intact SARS-CoV-2 includes coronavirus cross ...

T cell receptor (TCR) sequencing showed partial repertoire preservation after expansion. Resultant CD8 T cells recognize SARS-CoV-2–infected respiratory tract ...

T cell responses in patients with COVID-19 - Nature

Moreover, CD4+ T cells specific for the SARS-CoV-2 spike protein have been identified in acute infection and have a TH1 cell cytokine profile. A ...

T Cell Response to SARS-CoV-2 Coinfection and Comorbidities

In terms of infection, T cells secrete IFNγ, Granzyme B, and TNFα to help eliminate SARS-CoV-2 infected cells [16]. In mild COVID-19 patients, ...

Post-pandemic memory T cell response to SARS-CoV-2 is durable ...

Nesamari et al. investigate T cell responses in the context of hybrid immunity 3.5 years after the start of the. COVID-19 pandemic. They show ...

Understanding T cell responses to COVID-19 is essential ... - Science

The ideal goal would be to define protective T cell responses after infection or vaccination or both. ... The study concluded that individuals with SARS-CoV-2– ...

The prospect of universal coronavirus immunity - Frontiers

Cross-immunity between hCoVs and SARS-CoV-2 has not been well characterized. Here, we systematically investigated T cell responses against the immunodominant ...

[PDF] Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...

Semantic Scholar extracted view of "Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals" by A.

Profiling the SARS-CoV-2-specific T-cell response - The Lancet

SARS-CoV-2-specific T cells were previously associated with protection from symptomatic coronavirus disease-2019 (COVID-19) in children who were ...

T cell immunity to SARS-CoV-2 - ScienceDirect.com

A new study found that severe COVID-19 is not preferentially associated with the quantity of the CD4+ T cell response, but rather poor polyfunctionality and ...

T Lymphocytes as Targets for SARS-CoV-2 - SpringerLink

The decrease in the T cell functions in COVID-19 may be partly due to their non-productive infection with SARS-CoV-2, as well as non-infectious ...

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in ...

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals and Antibody responses to SARS-CoV2 are ...

Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed ...

A study on SARS-CoV-1 from 2008 (26) showed that T cell responses were mainly directed against the S protein and that CD8+ T-cell responses were ...

SARS-CoV-2-specific antibody and T-cell responses 1 year after ...

However, analyses of lymphocytes from COVID-19-convalescent individuals indicate that B cells and CD4 or CD8 T cells play an important role in ...