The Efficacy of Using Patient|Derived Organoids to Predict ...

The Efficacy of Using Patient-Derived Organoids to Predict ...

In the neoadjuvant setting, Lv et al. found that the response rate to chemoradiotherapy was significantly higher among patients with radio- ...

The Efficacy of Using Patient-Derived Organoids to Predict ...

The Efficacy of Using Patient-Derived Organoids to Predict Treatment Response in Colorectal Cancer. Cancers (Basel). 2023 Jan 28;15(3):805. doi: ...

Patient-derived organoids as a predictive biomarker for treatment ...

The clinical validity of using PDOs to predict treatment response should be confirmed in studies with a larger group of patients, ideally in ...

Using patient-derived organoids to predict locally advanced or ...

Predicting the clinical response to chemotherapeutic or targeted treatment in patients with locally advanced or metastatic lung cancer ...

Review Patient-derived organoids in precision cancer medicine

The organoids, tested with various immunotherapies, demonstrated a high success rate in mimicking clinical responses and were used to activate ...

Organoids and organs-on-chips: insights into predicting the efficacy ...

These advantages demonstrate the great potential for patient-derived organoids to develop personalized anticancer therapies, including ...

Patient-derived Organoid Model for Predicting the Chemoresponse ...

The response of the patients' organoids to chemotherapeutic agents was consistent with the response to chemotherapy actually performed in those patients with ...

Patient-derived organoids for precision oncology - BMC Cancer

Patient-derived organoids recapitulate the basic features of primary tumors, including histological complexity and genetic heterogeneity, which ...

Personalized drug screening using patient-derived organoid and its ...

Gastric cancer (GC) is the fifth most common cancer and the fourth most common cause of cancer death globally, and its incidence rate has ...

Patient-derived organoids can predict response to chemotherapy in ...

In a clinical study, the responses of organoids to irinotecan correlated with patients' responses to the drug, suggesting that organoids could ...

Patient-derived organoids in precision cancer medicine: Med

The device precisely controls the flow and concentration of the gel and medium through microchannels, ensuring a stable and dynamic environment ...

Patient-Derived Cancer Organoids as Predictors of Treatment ...

Organoids were able to predict the response to irinotecan-based therapies in more than 80% of patients without misclassifying patients who ...

Unlocking the potential of patient-derived organoids ... - UCLA Health

“Testing drugs with patient-derived tumor organoids has potential to help predict how a patient may respond to treatment, with the goal of ...

Patient-derived organoids as a platform for drug screening in ...

Results: The mCRC organoids were successfully established with an 80% success rate. The PDOs maintained the genetic and phenotypic heterogeneity ...

Patient-Derived Organoids Predict Chemotherapy Efficacy for ...

MW: This is the largest single institutional series of patient-derived organoids for pancreatic cancer reported to date. We delivered successful ...

Advancements in Research and Treatment Applications of Patient ...

Medium replacement is typically performed every 2–3 days. Every 1–2 weeks, PDTOs can be passaged, often using trypLE to dissociate the PDTOs into single cells ...

Patient-derived organoid (PDO) platforms to facilitate clinical ...

Numerous studies have reported the successful use of organoids to predict therapy response in cancer patients. Recently, organoids have been ...

Patient-derived organoids in human cancer: a platform for ...

The accuracy was determined to be 84.43%, with a sensitivity of 78.01%. The results also indicated a specificity of 91.97%, further highlighting ...

Spatio-Temporal Analysis of Patient-Derived Organoid Videos Using ...

Abstract:Over the last ten years, Patient-Derived Organoids (PDOs) emerged as the most reliable technology to generate ex-vivo tumor avatars ...

Establishment of patient‐derived organoids for guiding personalized ...

Using the culture system, we established 60 organoids from 75 breast samples, resulting in an overall success rate of 80.0% (n = 60/75). Of ...