The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

The genomic landscape of pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2754 ...

The genomic landscape of pediatric acute lymphoblastic leukemia ...

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer and constitutes approximately 25 % of cancer diagnoses among children ...

The genomic landscape of pediatric and young adult T-lineage ...

T-ALL constitutes up to 25% of acute lymphoblastic leukemia (ALL) cases and is subclassified according to the stage of thymic maturation, such ...

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Introduction: Although recent studies have refined the classification of B-progenitor and T-lineage acute lymphoblastic leukemia into ...

The genomic landscape of pediatric acute lymphoblastic leukemia ...

We summarize a decade of genomic discoveries to highlight three different facets of precision medicine in pediatric ALL.

The genomic landscape of pediatric acute lymphoblastic leukemia 3 ...

In this genomepaint view mutations for each gene are displayed by chromosome location and ALL subtype. The viewer is encouraged to enter the HUGO gene name of ...

The genomic landscape of acute lymphoblastic leukemia in children ...

Even in childhood ALL, which has been the most extensively sequenced, at least 11% of cases lack a known, leukemia-initiating chromosomal ...

Genomic landscape of pediatric B-other acute lymphoblastic ...

P80R was associated with a specific gene expression signature, potentially defining a novel leukemia subtype. Our study shows unbiased European ...

the genomic landscape of pediatric and young adult t-lineage acute ...

Using integrated genomic analysis of 264 T-ALL cases, 106 putative driver genes are identified and new mechanisms of coding and noncoding alteration are ...

The genomic landscape of pediatric acute lymphoblastic leukemia

Request PDF | The genomic landscape of pediatric acute lymphoblastic leukemia | Acute lymphoblastic leukemia (ALL) is the most common childhood cancer.

The genomic landscape of pediatric acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most coMultiple Myelomaon childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2,754 ...

The genomic landscape of pediatric and young adult T-lineage ...

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia. TARGET · TARGET-ALL · TARGET-ALL-P2. Nat Genet. Volume 49, Issue 8: p ...

Genomic landscape of childhood acute lymphoblastic leukemia

Genomic landscape of childhood acute lymphoblastic leukemia. Abstract in preparation. Type: Other; Archiver: European Genome-Phenome Archive (EGA). 2 Datasets.

Genomic landscape of childhood ALL: new analysis delves deeper ...

Charles Mullighan, MBBS, MD, St. Jude Children's Hospital, Memphis, TN, explains the genomic landscape of childhood acute lymphoblastic ...

The genomic landscape of high hyperdiploid childhood acute ...

High hyperdiploid (51-67 chromosomes) acute lymphoblastic leukemia (ALL) is one of the most common childhood malignancies, comprising 30% of all pediatric B ...

The Genomic Landscape of Pediatric Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer and most children with ALL will survive. Unfortunately, a small percentage of these ...

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Methods: We studied 2789 children, adolescents and young adults (AYA) with newly diagnosed B-ALL (n=2,322 cases) or T-ALL (n=467) treated on Children's Oncology ...

The genomic landscape of pediatric and young adult T-lineage ...

... childhood T-ALL (for example, CCND3 , CTCF , MYB , SMARCA4 ... The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia ...

Paper: The Genomic Landscape of Childhood T-Lineage Acute ...

Acute Lymphoblastic Leukemia: Biology, Cytogenetics and Molecular Markers in Diagnosis and Prognosis Program: Oral and Poster Abstracts

Hématologie - The genomic landscape of adult B-cell precursor ...

... pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell. 2002;1:133-143. 2; [3] Papaemmanuil E., Rapado I., Li Y. RAG-mediated ...