The Immune Microenvironment of Pancreatic Cancer

The Immune Microenvironment in Pancreatic Cancer - PMC

Recent data have resulted in a refined topography of the immune landscape that defines the pancreatic cancer microenvironment. It has become clear that complex ...

Tumour microenvironment of pancreatic cancer: immune landscape ...

The role of the immune microenvironment of pancreatic cancer as an important prognostic/predictive feature is starting to emerge. PDAC is ...

The Immune Microenvironment in Pancreatic Cancer - PubMed

The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment.

Tumor immune microenvironment-based therapies in pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor immune microenvironment (TIME) formed by ...

Pancreatic cancer tumor microenvironment is a major therapeutic ...

Desmoplasia is the hallmark of PDAC microenvironment that creates a physical and immunologic barrier. Stromal support cells and immunomodulatory cells face ...

An integrated overview of the immunosuppression features in the ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies. It is characterized by a complex and immunosuppressive tumor microenvironment (TME) ...

Pancreatic Tumor Microenvironment - ScienceDirect.com

The pancreatic TME is primarily comprised of cancer associated fibroblasts (CAFs) that secrete extracellular matrix (ECM) proteins to create a physical ...

Role of Immune Microenvironment in Pancreatic Ductal ... - MDPI

In fact, PDAC is considered a highly immunosuppressive and heterogeneous neoplasm, characterized by an immunosuppressive TME and a high ability ...

Dynamic profiling of immune microenvironment during pancreatic ...

Early pancreatic cancer still has a large number of active lymphocytes, which may be the window period for immunotherapy. Implications of all ...

Abstract A032: KRAS mutations have distinct effects on the tumor ...

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with abysmal survival rates. The highly immunosuppressive ...

655 Dissecting pancreatic cancer tumor-immune microenvironment ...

Conclusions Spatial transcriptomics and proteomics reveal insights into the spatial relationship between PDAC tumor cell EMT plasticity, CAFs, and immune ...

Spatial immune composition of tumor microenvironment in patients ...

This study examined the composition of the immune microenvironment at different sites within resected pancreas specimens from patients with ...

Effects of anoxic prognostic model on immune microenvironment in ...

Pancreatic cancer has one of the worst prognoses in the world, which suggests that the tumor microenvironment, which is characterized by ...

The Tumor Immune Microenvironment in Pancreatic Ductal ... - MDPI

Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic tumor and is associated with poor prognosis and treatment response.

The tumor immune microenvironment in resected treatment-naive ...

In conclusion, our study unveiled a distinctive yet intricate TIME associated with prolonged survival in pancreatic cancer. This profile ...

Immune microenvironment and immunotherapy in pancreatic cancer

With the study of the immune microenvironment of pancreatic cancer, it has been found that the inhibitory immune microenvironment of pancreatic cancer is ...

Remodeling of Stromal Immune Microenvironment by Urolithin A ...

Immunotherapeutic agents are ineffective against pancreatic cancer, mainly due to the immunosuppressive tumor microenvironment and stromal desmoplasia. Our ...

Pancreatic ductal adenocarcinoma immune microenvironment and ...

Abstract. The tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) is non-immunogenic, which consists of the stellate cells, ...

The Immune Microenvironment in Pancreatic Cancer

The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment. In this regard, pancreatic ...

Tumor Microenvironment in Pancreatic Cancer Pathogenesis and ...

Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment with remarkable cellular and spatial heterogeneity ...