- The need for new approaches in CNS drug discovery🔍
- The Need for New Approaches in CNS Drug Discovery🔍
- Advances in Drug Discovery for Central Nervous System Diseases🔍
- Innovative approaches in CNS clinical drug development🔍
- Phenotypic approaches for CNS drugs🔍
- Natural products in drug discovery🔍
- CNS Drug Discovery in Academia🔍
- Promising Paths To Accelerate the Drug Discovery Process🔍
The Need for New Approaches in CNS Drug Discovery
The need for new approaches in CNS drug discovery - PubMed
In this introduction we review some of the reasons for failure, delineating both scientific and technical realities, some unique to the CNS, that have ...
The Need for New Approaches in CNS Drug Discovery
CNS drugs in general have higher failure rates than non-CNS drugs, both preclinically and clinically, and in some areas, such as the major neurodegenerative ...
The need for new approaches in CNS drug discovery
CNS drug discovery and development has been problematic, particularly in the area of acute and chronic neurodegenerative disorders.
The need for new approaches in CNS drug discovery
CNS drug discovery and development has been problematic, particularly in the area of acute and chronic neurodegenerative disorders. ... These difficulties have ...
The need for new approaches in CNS drug discovery
Semantic Scholar extracted view of "The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes" by ...
Advances in Drug Discovery for Central Nervous System Diseases
Gribkoff and Leonard K. Kaczmarek, authors of an article in Neuropharmacology entitled “The need for new approaches in CNS drug discovery.” In ...
The Need for New Approaches in CNS Drug Discovery
Request PDF | The Need for New Approaches in CNS Drug Discovery: Why Drugs Have Failed, and What Can Be Done to Improve Outcomes | An important goal of ...
Innovative approaches in CNS clinical drug development
Integrated experimental medicine should increase the probability and predictability of success while controlling clinical trials costs. Finally, the societal ...
In rare disease, that means one disease can be classified into multiple ultra-rare diseases – all of them potential targets for new drugs. Researchers have also ...
Phenotypic approaches for CNS drugs - Cell Press
While most CNS drug discovery studies have employed chemogenomic-based compound libraries, new fragment-based approaches are emerging that offer ...
Natural products in drug discovery: advances and opportunities
NPs have long been the key source of new drugs against infectious diseases, especially antibiotics (reviewed elsewhere). Selected NPs with ...
CNS Drug Discovery in Academia: Where Basic Research Meets ...
Drug discovery targeting the central nervous system (CNS) is particularly challenging because it requires the combined skills of neuroscience ...
Innovative approaches in CNS clinical drug development - HAL
Neurological disorders are recognized as major causes of death and disability worldwide with high unmet medical needs. Neurological disorders ...
Promising Paths To Accelerate the Drug Discovery Process
We also highlight novel approaches to CNS drug discovery that leverage today's advances in genomics and epigenomics to generate treatments that are aimed at ...
current development of CNS drug research - Oxford Academic
Developing new CNS drugs is high risk because there is a relatively poor responder vs. non-responder ratio and a high failure rate, increasing the need for ...
Novel CNS drug discovery and development approach
Neurotransmitter receptors have been the typical target for many (classical) CNS drugs, while 'single target' pharmacological intervention and/ ...
The need for new approaches in CNS drug discovery - OUCI
The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes · List of references · Publications that cite ...
The Striking Technological Advances in Drug Development and ...
Developing new drugs for any disease is an expensive, time-consuming, and risky endeavor. This is especially true for central nervous system (CNS) disorders ...
Explaining Central Nervous System Protocols & Drug Development
This article explores the need for innovative therapies in the treatment of CNS disorders, the particularities of CNS protocols, and the challenges in CNS drug ...
Innovative approaches in CNS drug discovery | Request PDF
Request PDF | Innovative approaches in CNS drug discovery | Central nervous system disorders remain the leading causes of mortality and ...