The Role of Cellular Senescence in the Gastrointestinal Mucosa

The role of cellular senescence in the gastrointestinal mucosa

Cellular senescence is a biologically irreversible state of cell-growth arrest that occurs following either a replicative or an oncogenic ...

Cellular senescence is a biologically irreversible state of cell-growth arrest that occurs following either a replicative or an oncogenic ...

The Role of Cellular Senescence in the Gastrointestinal Mucosa

Cellular senescence is a biologically irreversible state of cell-growth arrest that occurs following either a replicative or an oncogenic ...

The Role of Cellular Senescence in the Gastrointestinal Mucosa

Senescent cells can be identified in vitro because they express senescence-associated β-galactosidase, a marker of increased lysosomal activity. Cellular ...

[PDF] The Role of Cellular Senescence in the Gastrointestinal Mucosa

The Senescence cascade and the cell-cycle checkpoints that dictate the progression and maintenance of senescence are important in all types of ...

A new face of old cells: An overview about the role of senescence ...

Cellular senescence is a pivotal factor contributing to aging and the pathophysiology of age-related diseases. Despite the presence of inflammation and ...

Comprehensive assessment of cellular senescence in intestinal ...

Therefore, evaluating the involvement of genes related to cellular senescence in UC intestinal inflammation and immunity helps elucidate the ...

The connection between aging, cellular senescence and gut ...

The intricate interplay between cellular senescence and alterations in the gut microbiome emerges as a pivotal axis in the aging process, ...

Cellular Senescence, Inflammation, and Cancer in the ... - MDPI

Figure 2. The effect of Helicobacter pylori infection and senescent cells on the mucosa of the stomach. H. pylori infection leads to oxidative ...

Summary of Mechanisms of Cellular Senescence in the ...

Cellular senescence is a biologically irreversible state of cell-growth arrest that occurs following either a replicative or an oncogenic stimulus.

Crosstalk between gut microbiota and cellular senescence - Cell Press

Long-term stimulation by gut bacteria induces cellular senescence of germinal center (GC) B cells in the ileum with aging. B cell senescence ...

ELMO1 ameliorates intestinal epithelial cellular senescence via ...

Deletion of ELMO1 led to senescent IECs accumulation and triggered premature fibrosis in murine colitis. Furthermore, irisin, inhibiting the ...

Role of cellular senescence in inflammation and regeneration

Cellular senescence is the state in which cells undergo irreversible cell cycle arrest and acquire diverse phenotypes.

Cellular senescence in lymphoid organs and immunosenescence

The goal of this review is to explore the role of cellular senescence in age-associated lymphoid organ dysfunction and immunosenescence.

Inflammation-Associated Senescence Promotes Helicobacter pylori ...

Gastric mucosa atrophy was highly associated with cellular senescence. H pylori promoted gastric epithelial cell senescence in vitro and in vivo in a manner ...

Emerging Interrelationship Between the Gut Microbiome and ...

It is thus evident that intestinal epithelial, as well as stem cells, exhibit age-dependent cellular senescence which can contribute to known ...

Cellular senescence in gastrointestinal diseases - ResearchGate

Request PDF | Cellular senescence in gastrointestinal diseases: From pathogenesis to therapeutics | Senescence is a durable cell cycle arrest that can be ...

Cellular senescence: Neither irreversible nor reversible

Cellular senescence is a critical stress response program implicated in embryonic development, wound healing, aging, and immunity.

The role of cellular senescence in skin aging and age-related skin ...

Moreover, senescent cells impair tissue homeostasis, promote inflammation and extracellular matrix (ECM) degradation by secreting molecules collectively known ...

The Role of Cellular Senescence in the Gastrointestinal Mucosa ...

The Role of Cellular Senescence in the Gastrointestinal Mucosa. Penfield J.D., Anderson M., Lutzke L., Wang K.K.. Expand. Publication type: Journal Article.