The Role of Genetic Testing in the Evaluation of Dilated ...

Approximately 30% to 50% of DCMs are due to familial cardiomyopathies with an identifiable genetic cause found in up to 40% of these, and ...

The Role of Genetic Testing in the Evaluation of Dilated ... - PubMed

We present an adolescent African American male admitted to the cardiac intensive care unit with cardiogenic shock and acute respiratory ...

The Genetic Evaluation of Dilated Cardiomyopathy - ScienceDirect

Genetic testing is often most useful to determine at risk family members and does not have a direct health benefit to the proband, although it can help to ...

Evidence-Based Assessment of Genes in Dilated Cardiomyopathy

The panel used the Clinical Genome Resource semiquantitative gene-disease clinical validity classification framework with modifications for DCM ...

(PDF) The Role of Genetic Testing in the Evaluation of Dilated ...

Through an overview of his presentation, diagnostic workup, and treatment, we demonstrate the clinical utility of genetic testing in the ...

Implications of Genetic Testing in Dilated Cardiomyopathy

Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical phenotypes are common in genetic DCM, but their exact ...

Diagnosing Familial Dilated Cardiomyopathy - Stanford Health Care

Based on the clinical features of a family's or patient's presentation of disease, our team will determine which genetic test, if any, is most appropriate. If a ...

The Genetic Evaluation of Dilated Cardiomyopathy - Structural Heart

Subsequently, these findings have increased adoption of genetic testing in the management of DCM, which has allowed for improved risk ...

The Role of Genetic Testing in the Evaluation of Dilated ...

Through an overview of his presentation, diagnostic workup, and treatment, we demonstrate the clinical utility of genetic testing in the evaluation of ...

A cost-effectiveness model of genetic testing and periodical clinical ...

A cost-effectiveness model of genetic testing and periodical clinical screening for the evaluation of families with dilated cardiomyopathy. Max Catchpool ...

The role of genetic testing in diagnosis and care of inherited cardiac ...

The diagnostic yield of genetic testing for inherited cardiac diseases is up to 40% and is primarily indicated for screening of at-risk ...

Importance of Genetic Testing in Dilated Cardiomyopathy - SciELO

Whole-exome sequencing: this approach covers “all” exons and flanking regions of the human genome (in practice, it considers only those genes for which ...

Considering complexity in the genetic evaluation of dilated ...

Clinicians now have expansive panels with many genes available for DCM genetic testing, and the approaches used to evaluate rare variants to decide which are ...

How to… conduct genetic testing for patients with DCM

Genetic testing for DCM aims to identify the (usually one) rare pathogenic genetic variant that is the primary causal factor for disease in a patient.

Review Clinical and genetic issues in dilated cardiomyopathy

The discovery of genetic cause for some of DCM, otherwise thought to be idiopathic, and the rapid development of more cost-effective molecular genetic testing ...

An intervention strategy to improve genetic testing for dilated ...

Despite its clinical implications in screening and therapy, genetic testing in dilated cardiomyopathy (DCM) is underused. This study evaluated ...

Screening for dilated cardiomyopathy in immediate family members

The recent ESC guidelines emphasize that age should not be a limiting factor in the use of genetic testing, considering the diagnostic ...

The Diagnosis and Evaluation of Dilated Cardiomyopathy

At present, routine genetic testing is only recommended in familial disease (≥2 affected family members) (15), where its diagnostic yield is 30% to 35%.

The Role of Genetic Testing in the Evaluation of Dilated ... - Typeset.io

The Role of Genetic Testing in the Evaluation of. Dilated Cardiomyopathies. Kolade M. Agboola ,. 1. Trevon McGill,. 2. Barry A. Boilson,. 1.

Dilated Cardiomyopathy Genetic Testing - DCM Foundation

Research shows that even when only one person in the family has DCM, the condition can still be genetic. There are different ways in which genetics can play a ...