The Role of the Interplay Between Autophagy and NLRP3 ...

The Role of the Interplay Between Autophagy and NLRP3 ... - Frontiers

In this review, we summarized the recent studies on the interplay between autophagy and NLRP3 inflammasome in metabolic disorders.

There are two mechanisms of the effects of autophagy on NLRP3 inflammasome: one is that autophagy inhibits NLRP3 inflammasome by scavenging ROS ...

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers

Autophagy can negatively regulate NLRP3 inflammasome activation by removing endogenous inflammasome activators, such as ROS-producing damaged mitochondria, ...

The Interplay between Autophagy and NLRP3 Inflammasome in ...

These suggested that NLRP3 inflammasomes played an important role in intestinal inflammation induced by I/R. During intestinal I/R, the ratio of LC3-II/I was ...

The Complex Interplay between Autophagy and NLRP3 ... - MDPI

It has been reported that the interplay between autophagy and NLRP3 inflammasome is involved in many diseases, including renal diseases. In this ...

The Interplay between Autophagy and NLRP3 Inflammasome in ...

Studies have shown that autophagy and the NLRP3 inflammasome play an important role in the process of I/R injury, but the relevant mechanisms ...

Interplay Between NLRP3 Inflammasome and Autophagy

Inflammasome signaling pathways can regulate autophagic process necessary for balance between required host defense inflammatory response and prevention of ...

Relationship between autophagy and NLRP3 inflammasome during ...

In conclusion, autophagy reduction and NLRP3 inflammasome activation in chondrocytes may be implicated in articular cartilage degradation, under estrogen- ...

Inflammaging: disturbed interplay between autophagy ... - Aging-US

NLRP3 activation is also enhanced in many age-related diseases, e.g. atherosclerosis, obesity and type 2 diabetes. NLRP3 activates inflammatory caspases, mostly ...

The Role of the Interplay Between Autophagy and NLRP3 ... - Altmetric

Readers on ; The Role of the Interplay Between Autophagy and NLRP3 Inflammasome in Metabolic Disorders · Frontiers in Cell and Developmental Biology, March 2021.

The role of vitamin D3 in modulating the interplay between NLRP3 ...

NLRP3 inflammasome overactivation parallels compromised autophagy in NASH. ... CAL regulates de novo lipogenesis in NASH as evidenced by curbed SREBP1c levels.

Small molecule-driven NLRP3 inflammation inhibition via interplay ...

Mechanically, Ka promoted macroautophagy/autophagy in microglia, leading to reduced NLRP3 protein expression, which in turn deactivated the NLRP3 inflammasome.

Crosstalks between inflammasome and autophagy in cancer

In general, autophagy is regarded as a safety mechanism counteracting hyperactivation of inflammasomes and chronic inflammation-induced cancer [ ...

The Complex Interplay between Autophagy and NLRP3 ... - OUCI

Autophagy is a highly conserved process of the eukaryotic cell cycle. It plays an important role in the survival and maintenance of cells by degrading ...

Two mechanisms of the effects of autophagy on NLRP3 ...

... Elucidating the interplay between pyroptosis and autophagy may shed light on novel biological mechanisms and therapeutic approaches. Autophagic clearance of ...

The Role of the Interplay Between Autophagy and NLRP3 ...

It is involved in many diseases. In recent years, the interplay between autophagy and NLRP3 inflammasome has been reported to contribute to many diseases ...

The Role of HDAC6 in Autophagy and NLRP3 Inflammasome.

The association between autophagy and inflammasomes was discovered more than ten years ago. Satioh et al. first reported the interplay between autophagy and the ...

disturbed interplay between autophagy and inflammasomes | Aging

NLRP3 activation is also enhanced in many age-related diseases, e.g. atherosclerosis, obesity and type 2 diabetes. NLRP3 activates inflammatory caspases, mostly ...

Interaction among inflammasome, autophagy and non-coding RNAs

As an important component of innate immunity, NLRP3 plays an important role in both immune response and a variety of disease processes17, ...

Interplay Between NLRP3 Inflammasome and Autophagy

The NLRP3 inflammasome is cytosolic multi-protein complex that induces inflammation and pyroptotic cell death in response to both pathogen (PAMPs) and ...