The SAGA chromatin|modifying complex

The SAGA chromatin-modifying complex: the sum of its ... - PubMed

There are many large protein complexes involved in transcription in a chromatin context. However, recent studies on the SAGA coactivator ...

The SAGA chromatin-modifying complex: the sum of its parts is ...

The SAGA complex contains TBP-associated factors. Transcription initiation requires the assembly of the preinitiation complex (PIC), formed by ...

Conservation and diversity of the eukaryotic SAGA coactivator ...

Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in Drosophila gene expression and development. Genes Dev. 2017 ...

Dynamic modules of the coactivator SAGA in eukaryotic transcription

SAGA (Spt-Ada-Gcn5 acetyltransferase) is a eukaryotic transcription coactivator complex that controls transcription by modifying histones. The ...

Structure of the human SAGA coactivator complex - Nature

The SAGA complex is a regulatory hub involved in gene regulation, chromatin modification, DNA damage repair and signaling.

The SAGA unfolds: convergence of transcription regulators in ...

Accordingly, chromatin structures are remodelled prior to or during transcriptional activation1, 2. A number of large protein complexes (such as Swi–Snf[3]), ...

SAGA Complex - The Nogales Lab

In eukaryotes, the expression of protein-coding genes involves the integration of cellular signals, chromatin modification, and assembly of the ...

The biochemical and genetic discovery of the SAGA complex

This strengthened the connection between chromatin structure and transcriptional regulation, as Swi and Snf proteins were initially identified as ...

The SAGA complex regulates early steps in transcription via its ...

Loss of USP22 results in deficient Mediator tail‐module recruitment to target gene promoters, and alters the long‐range chromatin interaction landscape between ...

Interplay between transcriptional regulators and the SAGA ...

Interplay between transcriptional regulators and the SAGA chromatin modifying complex fine-tune iron homeostasis. Manjit Kumar Srivastav.

The SAGA histone acetyltransferase module targets SMC5/6 to ...

The SMC complexes play roles in all key chromatin processes, including cohesion, condensation, replication, transcription and DNA repair. Their ...

X Li: Enzymatic modules of the SAGA chromatin-modifying complex ...

"Xuanying Li (Stowers Institute for Medical Re) presents 'Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in ...

SAGA complex | SGD - Saccharomyces Genome Database

This opens up the chromatin landscape for binding of additional transcription factors and the pre-initiation complex. The DUB module facilitates elongation ...

The SAGA chromatin-modifying complex: the sum of its parts is ...

This review focuses on one of the first identified chromatin-modifying complexes, the Spt/Ada/ Gcn5 acetyltransferase (SAGA) complex. We ...

Insights into SAGA function during gene expression | EMBO reports

Histone modifications are a crucial source of epigenetic control. SAGA (Spt–Ada–Gcn5 acetyltransferase) is a chromatin‐modifying complex that contains two ...

The SAGA chromatin-modifying complex: the sum of its parts is ...

The initial discovery of the canonical SAGA complex, the subsequent studies that have shaped the view on the internal organization of its ...

The KAT module of the SAGA complex maintains the oncogenic ...

We demonstrate that loss of SAGA complex KAT activity is associated with reduced MYCN binding on chromatin, suppression of MYC/MYCN gene expression programs, ...

The SAGA chromatin-modifying complex: The sum of its parts is ...

PDF | There are many large protein complexes involved in transcription in a chromatin context. However, recent studies on the SAGA coactivator complex.

Targeting the SAGA and ATAC Transcriptional Coactivator ...

GCN5 (KAT2A) was later identified as a component of the ADA Two A Containing (ATAC) complex, which also regulates gene transcription and chromatin organization ...

Role of the SAGA co-activator complex in transcription during cell ...

... chromatin structure at promoters to facilitate the assembly of the preinitiation complex, composed of general transcription factors and RNAPII. SAGA is a ...