The Shu complex is a conserved regulator of Rad51 filament formation

The Shu complex is a conserved regulator of homologous ... - PubMed

... cancer predisposition. A key step in HR is the formation of Rad51 nucleoprotein filaments wh …

The Shu complex is a conserved regulator of homologous ...

The budding yeast Shu complex is a heterotetramer (Shu1, Shu2, Csm2 and Psy3) that promotes HR by regulating a key step of HR, the formation of Rad51 filaments ...

The Shu complex is a conserved regulator of Rad51 filament formation

The Shu complex is a conserved regulator of Rad51 filament formation by. Stephen Kenneth Godin. B.S. Biology, University of Massachusetts ...

The Shu complex is a conserved regulator of Rad51 filament formation

Abstract. The budding yeast Shu complex, a heterotetramer of Shu1, Shu2, Csm2, and Psy3, is important for homologous recombination ...

Shu complex is an ATPase that regulates Rad51 filaments ... - bioRxiv

The yeast Shu complex (Shu) is a conserved regulator of HR, working through its modulation of Rad51 filaments.

Structural basis for the functional role of the Shu complex in ...

These data indicate that the Shu complex might be a conserved regulator in the formation of Rad51–ssDNA filament in eukaryotes. In the Shu ...

The human Shu complex promotes RAD51 activity by modulating ...

... RAD51 filament formation and template switching (Fig. 6). Here we ... Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti- ...

The Shu complex prevents mutagenesis and cytotoxicity of single ...

The Shu complex promotes Rad51 filament formation, a key step for HR ... (2016) The Shu complex is a conserved regulator of homologous ...

The Shu complex, which contains Rad51 paralogues, promotes ...

Last, we show that Shu1 regulation of Srs2 to double-strand breaks is not restricted to the rDNA, indicating a more general function for the Shu ...

human Shu complex functions with PDS5B and SPIDR to promote ...

... RAD51 filament formation from FIGNL1 anti-recombinase activity (29). It is possible that this might represent a conserved mechanism as we ...

Promotion of presynaptic filament assembly by the ensemble of S ...

... the Shu complex to promote Rad51 filament formation and homology directed repair ... Regulation of Rad51 presynaptic filament formation is ...

Shu complex is an ATPase that regulates Rad51 filaments in ...

The yeast Shu complex (Shu) is a conserved regulator of HR, working through its modulation of Rad51 filaments. However, the biochemical ...

Rad51 filament dynamics and its antagonistic modulators

Rad51 recombinase is the central player in homologous recombination, the faithful repair pathway for double-strand breaks and key event during meiosis.

Structural and SAXS analysis of the budding yeast SHU‐complex ...

The roles of the SHU-complex proteins were further investigated by mutagenesis with other homologous recombination repair (HRR) genes Rad51, ...

Structural Analysis of Shu Proteins Reveals a DNA Binding Role ...

As with Rad51, the Shu complex appears to form a nucleoprotein filament by binding nonspecifically to DNA. Structure-based mutagenesis studies have demonstrated ...

The Shu complex, which contains Rad51 paralogues, promotes ...

... Rad51 filaments against Srs2, but facultative for filament formation ... The Shu complex is a conserved regulator of homologous recombination.

The Rad51 paralog complex Rad55-Rad57 acts as a molecular ...

... conserved Rad51 paralogs help maintain genome integrity through their regulation of Rad51 filament assembly. ... Rad51 filament formation. Nature. 2011; 479 ...

assembly and disassembly of the Rad51 nucleoprotein filament in ...

POSITIVE REGULATORS OF RAD51 NUCLEOPROTEIN FILAMENT FORMATION ... Another factor that participates in Rad51 filament assembly is the Shu complex.

Sws1 is a conserved regulator of homologous recombination in ...

Formation of a Rad51 nucleoprotein filament, a process dependent on Rad52 ... This complex is conserved in humans, and it may be related to the Shu ...

The Shu complex interacts with Rad51 through the Rad51 ... - OUCI

List of references. Martin, Sws1 is a conserved regulator ... Rad51 filament formation, Nature, № 479, с. 245 ... Seong, Regulation of Rad51 recombinase presynaptic ...