The cellular protein phosphatase 2A is a crucial host factor for ...

Our study elucidates the crucial role of host protein phosphatase 2A (PP2A) in Marburg virus (MARV) transcription.

PP2A Phosphatase as an Emerging Viral Host Factor - PMC

Protein phosphatase 2A (PP2A) is one of the most ubiquitous cellular proteins and is responsible for the vast majority of Ser/Thr ...

Protein phosphatase 2A: a definite player in viral and parasitic ...

It is critical for viruses and parasites to successfully develop the means to interfere with key regulatory pathways in infected cells in order to ensure their ...

B′-protein phosphatase 2A is a functional binding partner of delta ...

Herein, cellular serine/threonine protein phosphatase 2A (PP2A) is identified as a functional IN binding partner exclusive to δ-retroviruses, ...

Protein phosphatase 2A is a critical regulator of protein kinase C ζ ...

Protein phosphatase 2A (PP2A), a major protein serine/threonine phosphatase in most mammalian tissues, is implicated in the regulation of various cellular ...

Phosphoprotein Phosphatase 2 - an overview | ScienceDirect Topics

Protein phosphatase 2 (PP2A) is a cellular serine-threonine phosphatase that negatively regulates oncogenic signaling, apoptotic signaling, and cell cycle ...

Protein phosphatase 2A has an essential role in promoting ... - PNAS

Ser/Thr phosphorylation is critical for T cell receptor signal transduction as well as cell survival/death regulation in developing ...

PP2A Phosphatase as an Emerging Viral Host Factor - OUCI

Protein phosphatase 2A (PP2A) is one of the most ubiquitous cellular proteins and is responsible for the vast majority of Ser/Thr phosphatase activity in ...

Protein Phosphatase 2A: Role in T Cells and Diseases - Roy - 2023

PP2A negatively regulates the AKT pathway by interfering with AKT phosphorylation at threonine-308, which is essential for AKT activation ...

Structural basis of protein phosphatase 2A stable latency - Nature

The catalytic subunit of protein phosphatase 2A (PP2Ac) is stabilized in a latent form by α4, a regulatory protein essential for cell ...

Pathogen protein modularity enables elaborate mimicry of a host ...

1 Each Phytophthora genome encodes hun- dreds of effectors that are essential for disease development.2–4. The effector repertoires exhibit a ...

Cellular Protein Phosphatase 2A Regulates Cell Survival ... - MDPI

Here, we show, by using knockdown and inhibition approaches of the catalytic subunit PP2Ac, that this phosphatase is important for efficient replication of ...

Protein phosphatase 2A regulates life and death decisions via Akt in ...

Polyoma Small T Induced Apoptosis in the Presence of Growth Factors. To study how small T antigens could affect host cell survival, we obtained cells ...

Roles and regulation of protein phosphatase 2A (PP2A) in the heart

Protein phosphatases (PP) are critical for regulation of signaling in heart. •. Altered PP2A activity is associated with heart failure and arrhythmia. •. PP2A ...

Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor ...

The serine/threonine phosphatase protein phosphatase 2A (PP2A) plays an essential role in many aspects of cellular functions and has been shown to be an ...

PP2A Phosphatase as an Emerging Viral Host Factor

... crucial role for oncogenic viruses, which utilize PP2A to transform ... Protein phosphatase 2A (PP2A) is one of the most ubiquitous cellular proteins ...

Protein phosphatases in the regulation of mitosis

Nilsson reviews the essential role of phosphoprotein phosphatases in the regulation of controlled dephosphorylation during cell division.

Critical Role for Protein Phosphatase 2A Heterotrimers in ...

Critical Role for Protein Phosphatase 2A Heterotrimers in Mammalian Cell Survival* ... We used TR-expressing PC6-3 cells as a host for the inducible RNAi cassette ...

PPP2R1A - Serine/threonine-protein phosphatase 2A 65 ... - UniProt

... essential for regulatory T-cells (Treg) homeostasis and stability (By similarity). Part of the striatin-interacting phosphatase and kinase ...

Protein phosphatase 2A – structure, function and role in ...

PP2A is responsible for at least 50% of total Ser/Thr dephosphorylation in most cell types and is predominantly found as trimeric holoenzymes ...