The clinical progress of mRNA vaccines and immunotherapies

Here we review the clinical progress of mRNA therapy as well as provide an overview and future outlook of the transformative technology behind these mRNA-based ...

Evolution and Progress of mRNA Vaccines in the Treatment of ...

Given that immunotherapy has been the cornerstone of melanoma treatment over the last several decades, further innate immunity enhancement by ...

mRNA-based vaccines and therapeutics: an in-depth survey of ...

Unfortunately, progress in clinical studies was stalled because of low mRNA ... The clinical progress of mRNA vaccines and immunotherapies. Nat ...

Investigational mRNA Vaccine Induced Persistent Immune ...

Chemotherapy, radiation, targeted therapy, and current immunotherapies are also largely ineffective against pancreatic cancer, so new therapies ...

Full article: Recent progress in mRNA cancer vaccines

TAAs, being non-mutated self-antigens, can lead to poor T cell responses and immune tolerance in clinical immunotherapy. Additionally, TAA expression in normal ...

The clinical progress of mRNA vaccines and immunotherapies - OUCI

The clinical progress of mRNA vaccines and immunotherapies. https://doi.org/10.1038/s41587-022-01294-2 ·. Journal: Nature Biotechnology, 2022, № 6, p. 840-854.

Advances and prospects of mRNA vaccines in cancer immunotherapy

The unique immunosuppressive state of the tumor microenvironment (TME) attracts much attention in the field of cancer therapy. Cancer immunotherapy aims to ...

Recent advances in mRNA cancer vaccines - Frontiers

In view of therapeutic mRNA cancer vaccines are undergoing early stages of clinical development ... The clinical progress of mRNA vaccines and immunotherapies.

mRNA-based therapeutics: looking beyond COVID-19 vaccines

Advances in the development of personalized neoantigen-based therapeutic cancer vaccines ... The clinical progress of mRNA vaccines and immunotherapies. Nat ...

Delivering the next generation of cancer immunotherapies with RNA

The excitement surrounding mRNA vaccines is reflected in the clinical landscape—since 2021, 10 mRNA cancer vaccine clinical trials have been initiated (Table 1) ...

mRNA: A promising platform for cancer immunotherapy

Clinical development of mRNA cancer vaccines. Numerous clinical trials on mRNA-based cancer vaccines have been conducted for multiple types of cancers. The ...

How mRNA Vaccines Might Help Treat Cancer - NCI

“There's a lot of synergy between research on immunotherapy and mRNA cancer vaccines,” said Robert Meehan, M.D., senior director of clinical ...

Progress and prospects of mRNA-based drugs in pre-clinical and ...

Application of mRNA vaccine in immunotherapy. a Types of COVID-19 vaccines in clinical trials (from WHO; March 30, 2023). b mRNA-based drugs ...

Responses of patients with cancer to mRNA vaccines depend on the ...

The rapid development and clinical testing of COVID-19 mRNA vaccines were ... Selected clinical trials of mRNA vaccines for cancer immunotherapies. The ...

Three-year Phase 1 Follow-Up Data for mRNA-based Individualized ...

... mRNA cancer vaccine approach in this indication with an unmet medical need. ... Based on its deep expertise in mRNA vaccine development and in- ...

Clinical advances and ongoing trials of mRNA vaccines for cancer ...

... development of mRNA vaccines during the ... vaccine manufacture methods, renders mRNA vaccines a promising option for cancer immunotherapy.

The clinical progress of mRNA vaccines and immunotherapies

The clinical progress of mRNA vaccines and immunotherapies. Overview of attention for article published in Nature Biotechnology, May 2022. Altmetric Badge ...

mRNA Vaccines: The Dawn of a New Era of Cancer Immunotherapy

Despite remarkable progress in oncology, malignant tumors remain the second leading cause of mortality worldwide (1). Conventional clinical treatments for ...

Therapeutic Vaccination and Cancer Immunotherapy

... progress and escape the host's immune system ... Currently, Moderna has several mRNA vaccines in different phases of clinical development ...

Immune Response to Investigational RNA Vaccine for Pancreatic ...

“Chemotherapy, radiation, targeted therapy, and current immunotherapies are also largely ineffective in pancreatic cancer, so new therapies are ...