The development of natural and designed protein nanocages for ...

This review presents several types of natural protein nanocages from source, structure, function to their physicochemical properties

Designed proteins induce the formation of nanocage-containing ...

Here we describe the design of self-assembling protein nanocages that direct their own release from human cells inside small vesicles in a manner that ...

Engineering protein nanocages as carriers for biomedical applications

Viruses have thus been an inspiration in developing diverse self-assembling protein nanocages from natural sources. ... design and development ...

Design of Ligand-Operable Protein-Cages That Open Upon Specific ...

Protein nanocages have diverse applications in medicine and ... We demonstrate these design principles using both a natural and a designed protein ...

Designed Protein Nanocages Inspired by Nature

Nature provides many examples of self-assembling molecular machines, including icosahedral protein cages that serve as compartments for ...

Redesign of protein nanocages: the way from 0D, 1D, 2D to 3D ...

... natural protein nanocages. This review outlines the recent advances in the field of the design and construction of artificial protein nanocages ...

Designed proteins assemble antibodies into modular nanocages

The combination of the wide range of receptor binding antibodies and natural ligands with the AbC methodology developed here in principle allows ready and ...

Manufacturing of non-viral protein nanocages for biotechnological ...

The development of natural and designed protein nanocages for encapsulation and delivery of active compounds. ... Designed proteins induce the formation of ...

Investigating Designed Protein Nanocages as a Modular Platform ...

Author(s): Lee, Eric Jinsuk | Advisor(s): Yeates, Todd O | Abstract: Protein nanocages are abundant throughout nature, comprising many different shapes, ...

Thermostability of protein nanocages: the effect of natural extra ...

The development of natural and designed protein nanocages for encapsulation and delivery of active compounds · Materials Science, Chemistry · 2021.

Nanoreactor Design Based on Self-Assembling Protein Nanocages

... nature, bioengineers have developed a variety of self-assembling supramolecular protein cages for use as biosynthetic nanoreactors that mimic ...

Protein nanocages pave the way for effective mRNA therapeutics

PNCs like MS2, Qβ, and PP7, developed from bacteriophages (viruses that target bacteria), are examples of natural protein assemblies capable of ...

Nanopore-Controlled Dual-Surface Modifications on Artificial Protein ...

The development of natural and designed protein nanocages for encapsulation and delivery of active compounds. Food Hydrocolloids 2021, 121 ...

Design and Functionalization of Natural and Synthetic Protein ...

... developing of an immunosorbent nanoparticle with clinical applications ... Design and Functionalization of Natural and Synthetic Protein Nanocages. 2023.

Shape‐Anisotropic Assembly of Protein Nanocages with Identical ...

Most of the designed crystalline protein nanocage materials are devoid of direction-controlled assembly and dynamic conversion, which is a key ...

Large Protein Nanocages Could Improve Drug Design and Delivery

... Nature last month by the same team describing the creation of the first designed icosahedron made of 60 copies of a single protein subunit.

Expanding protein nanocages through designed symmetry-breaking

with the control afforded by computational protein design should enable the creation of a ... Nature 535, 136–139 (2016). 9. Y.-T. Lai, D. Cascio, T. O. ...

King Lab | Research

Votteler J, Ogohara C, Yi S, Hsia Y, Nattermann U, et al. (2016) Designed proteins induce the formation of nanocage-containing extracellular vesicles. Nature ...

mRNA Delivery Systems Based on Protein Nanocages: How Far ...

... natural PNCs, and artificially designed PNCs (Fig. 1). The characteristics ... Evolution of a designed protein assembly encapsulating its own RNA genome.

Designed proteins induce the formation of nanocage-containing ...

Designed proteins induce the formation of nanocage-containing extracellular vesicles. November 2016; Nature 540(7632). DOI:10.1038/nature20607. Authors:.