The diagnostic work up of genetic and inflammatory dilated ...

The cardiomyopathy is considered dilated if the following criteria can be observed 1) left ventricular end-diastolic diameter (LVEDd) > 117% of ...

Myocardial Inflammation as a Manifestation of Genetic ...

M-Infl resembling myocarditis on imaging and histology occurs frequently as a clinical manifestation of classically genetic cardiac diseases, including dilated ...

Dilated Cardiomyopathy: A Comprehensive Approach to Diagnosis ...

A positive family history can be detected in up to 30–50% of DCM cases, and a causative genetic mutation can be identified in up to 40% of DCM ...

Dilated Cardiomyopathy (DCM) Workup - Medscape Reference

Lymphocytic myocarditis is the most common finding in human cardiac tissue biopsy specimens. Myocyte necrosis, degeneration, or both with ...

The Diagnosis and Evaluation of Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is best understood as the final common response of myocardium to diverse genetic and environmental insults. A rigorous work-up can ...

Dilated cardiomyopathy | Nature Reviews Disease Primers

Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or biventricular dilation and impaired contraction ...

The Diagnosis and Evaluation of Dilated Cardiomyopathy

A rigorous work-up can exclude alternative causes of left ventricular (LV) dilation and dysfunction, identify etiologies that may respond to specific treatments ...

Results of comprehensive diagnostic work-up in 'idiopathic' dilated ...

We show that extensive diagnostic testing beyond patient history, physical examination, routine blood tests, echocardiography and coronary angiography has a ...

Dilated Cardiomyopathy | Circulation Research - AHA Journals

Because of the large number of genes and alleles attributed to DCM, comprehensive genetic testing encompasses ever-increasing gene panels.

Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy

The study aimed to determine cardiac inflammation in a cohort of genetic DCM patients and investigate whether it associated with a younger disease onset.

Diagnostic Work-Up and Risk Stratification in X-Linked Dilated ...

Patients underwent endomyocardial biopsy (EMB). Genetic testing employed multiplex polymerase chain reaction and multiple ligation dependent probe assay for ...

Current Diagnostic and Treatment Strategies for Specific Dilated ...

The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation ...

Dilated cardiomyopathy and chronic cardiac inflammation ...

Dilated cardiomyopathy (DCM) is typically defined by left ventricular dilation and systolic dysfunction in the absence of a clear ...

KEY MESSAGES on Dilated Cardiomyopathy

4.2 Diagnostic work-up according to age ... Genetic testing is recommended in the presence of a familial form of DCM OR in sporadic DCM with clinical clues.

Diagnosis and Evaluation of Dilated Cardiomyopathy

... the diagnostic workup of DCM. Routine genetic testing is only recommended in familial disease (≥2 affected family members), where its ...

Dilated cardiomyopathy in the era of precision medicine

Familial evaluation is critical in the diagnostic workup of patients with DCM as it allows the identification of relatives with clinical or ...

Diagnosis and Risk Prediction of Dilated Cardiomyopathy in the Era ...

Work-up and risk stratification of DCM is clinically challenging, as there is great heterogeneity in phenotype and genotype. Throughout the last decade, ...

Screening for dilated cardiomyopathy in immediate family members

If genetic analysis has not been performed or has not identified a genetic cause in the family, follow-up of all first-degree relatives, ...

Dilated Cardiomyopathy (DCM) - Medscape Reference

Diagnosis. The workup in a patient with suspected cardiomyopathy may include the following: Complete blood count. Comprehensive metabolic panel.

Current Pathophysiological and Genetic Aspects of Dilated ...

The diagnostic work up of genetic and inflammatory dilated cardiomyopathy. e-Journal of the ESC Council for Cardiology Practice. 2015; 13 (19); 47. Munguti ...