The dose response principle from philosophy to modern toxicology

Paracelsus recognized that toxicity occurred due to specific chemicals, and the body's response to the chemicals depended on the dose. Paracelsus reasoned that ...

Since ancient times the concept of dose response, from a toxicological perspective, has been a matter of concern. Already by the 8th century ...

The dose response principle from philosophy to modern toxicology ...

The concept of dose response traces back to 8th century BC, with Hesiod's Harmonia. Mithridates VI Eupator was the first to approach the notion of dose ...

The dose response principle from philosophy to modern toxicology

pharmacology and toxicology. ... siologist Arthur Robertson Cushny (1866–1926). ... Harnack attempted to state descriptions regarding tolerance ...

The dose response principle from philosophy to modern toxicology ...

... modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science ... dose as a summary measure in quantifying toxic response ...

(Open Access) The dose response principle from philosophy to ...

The dose response principle from philosophy to modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science. Aristidis ...

History of dose response - J-Stage

Regulatory Toxicology and Pharmacology. 2016, Vol.80, p.9. Jialan Cao, Dana Kürsten, Steffen Schneider, et al. Uncovering toxicological complexity by multi- ...

The dose response principle from philosophy to modern toxicology ...

The dose response principle from philosophy to modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science. A. Tsatsakis 1.

Shedding light on Dose-Response and Dry Needling

Tsatsakis AM, Vassilopoulou L, Kovatsi L, et al. The dose response principle from philosophy to modern toxicology: The impact of ancient ...

Editorial overview: Hormesis and dose-response - ScienceDirect

Tsatsakis et al. The dose response principle from philosophy to modern toxicology: the impact of ancient philosophy and medicine in modern toxicology science ...

History of dose response. | Semantic Scholar

The dose response principle from philosophy to modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science · A. Tsatsakis ...

The Emergence of the Dose–Response Concept in Biology and ...

A historical assessment of the origin of the dose–response in modern toxicology and its integration as a central concept in biology and medicine is ...

Reevaluation of the Fundamental Dose–Response Relationship

The shape of the dose–response curve for toxic substances has been the topic of an enormous debate that began several decades ago and continues today ...

Toxicology rewrites its history and rethinks its future: Giving equal ...

In effect, modern medicine and its pharmacological and toxicological ... dose–response concept into the mainstream of pharmacology and toxicology.

The dose response principle from philosophy to modern toxicology

The dose response principle from philosophy to modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science. ; Date Published ...

DOSE-RESPONSE RELATIONSHIPS IN TOXICOLOGY

The science of toxicology is based on the principle that there is a relationship between a toxic reaction (the response) and the amount of poison received (the ...

Principles of dose-setting in toxicology studies: the importance of ...

Modern advancements in pharmacology and toxicology have revealed that the rates and mechanisms by which organisms absorb, distribute ...

“The dose makes the poison”: Key implications for mode of action ...

An important function of the practice of toxicology is to identify potential toxicological hazards through a broad spectrum of toxicity testing protocols. The ...

When a little bit of poison is good for you: Inside the theory of dose ...

... doses before crossing a threshold toward toxicity, or overdose. In modern medicine, dose response theory is foundational for both toxicology ...

John William Trevan's concept of Median Lethal Dose (LD50/LC50)

... response, hence assessing the complete spectrum of toxicity ... modern toxicology: The impact of ancient philosophy and medicine in modern toxicology science.