The heterogeneity and clonal evolution analysis of the advanced ...

Our findings revealed potential genetic regulators to predict the castration resistance and provide insights into the castration resistance ...

Clonal evolution and heterogeneity in advanced systemic ... - PubMed

Mastocytosis, Systemic* / genetics; Proto-Oncogene Proteins c-kit / genetics; Sequence Analysis, DNA. Substances. Proto-Oncogene Proteins c-kit.

Clonal evolution and heterogeneity in advanced systemic ...

In contrast to traditional bulk DNA sequencing (DNA-seq), genomic analysis at single-cell resolution may provide a better opportunity to resolve ...

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the ...

We review data and technologies that have revealed intra-tumor heterogeneity across cancer types and the dynamics, constraints, and contingencies inherent to ...

Prostate Cancer | The heterogeneity and clonal evolution analysis of ...

At present, androgen deprivation therapy (ADT) is the primary treatment of advanced prostate cancer. However, after several years of ADT, most ...

Intratumor genetic heterogeneity and clonal evolution to decode ...

Analyzing different tumor regions by next generation sequencing allows the assessment of intratumor genetic heterogeneity (ITGH), ...

Clonal evolution and heterogeneity in advanced systemic ...

In contrast to traditional bulk DNA sequencing (DNA-seq), genomic analysis at single-cell resolution may provide a better opportunity to resolve clonal ...

Intratumor heterogeneity and clonal evolution revealed in castration ...

Intratumor heterogeneity and clonal evolution revealed in castration-resistant prostate cancer by longitudinal genomic analysis ... Part II: treatment of advanced ...

Genetic Heterogeneity and Clonal Evolution Underlying ...

Fluorescence in situ hybridization analysis with probes specific to metastatic clones usually failed to find such cells in the primary tumor sample. In ...

Intratumoral heterogeneity and clonal evolution in liver cancer - Nature

... advanced stages, the almost inevitable emergence of drug ... Our survival analysis reveals that regional transcriptional heterogeneity ...

Reconstructing tumor clonal heterogeneity and evolutionary ...

Clonal evolution analysis of tumors in three triple-negative breast cancer (TNBC) patients. (A) RETCHER inferred three subclonal clusters from ...

Tumor Evolution, Heterogeneity, and Therapy for Our Patients With ...

... heterogeneity in primary and advanced cancers. The digital nature of high ... heterogeneity and clonal evolution. Therapy can drive cancers down new ...

The clonal evolution of metastatic colorectal cancer - Science

There exists no study in mCRC that evaluated the clonal heterogeneity and evolution ... Google DeepMind releases code behind its most advanced ...

Unmasking tumor heterogeneity and clonal evolution by single-cell ...

Single-cell analysis is a powerful tool to resolve ITH of solid tumors and to detect the genetic makeup of rare cancer cells such as circulating tumor cells ( ...

Clonal Evolution in Cancer - Mission Bio

See how single-cell analysis can advance your research. CANCER & SINGLE-CELL ... Clonal Evolution Drives Tumor Heterogeneity. The path to cancer is ...

Intratumoral Heterogeneity and Clonal Evolution Induced by HPV ...

High-resolution analysis of genomic rearrangements at human papillomavirus (HPV) integration sites reveals heterocateny, which implicates ...

Clonal Evolution Models of Tumor Heterogeneity - ASCO Publications

Cancer evolutionary biology is the study of the history of a tumor and the processes that have shaped its diversity. The major aim of this review is to ...

Clonal Heterogeneity and Tumor Evolution: Implications for Cancer ...

We hope this Research Topic will advance our understanding of ... Please note: Manuscripts consisting solely of bioinformatics, computational analysis ...

Clonal evolution and heterogeneity in advanced systemic ...

Request PDF | On Mar 23, 2021, Ken-Hong Lim and others published Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by ...

Clonal Evolution and Heterogeneity of Osimertinib Acquired ...

Results. We enrolled 34 patients with histologically confirmed EGFR mutant advanced lung adenocarcinoma in a prospective phase II clinical trial ...