The landscape of tolerated genetic variation in humans and primates
The landscape of tolerated genetic variation in humans and primates
We aimed to annotate these variants as being unlikely to cause human disease as they are tolerated by natural selection in a closely related species.
The landscape of tolerated genetic variation in humans and primates
Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical ...
The landscape of tolerated genetic variation in humans and primates
The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed.
The landscape of tolerated genetic variation in humans and primates
The landscape of tolerated genetic variation in humans and primates. Science. 2023 Jun 2;380(6648):eabn8153. doi: 10.1126/science.abn8197. Epub 2023 Jun 2. PMID ...
The landscape of tolerated genetic variation in humans and primates
We developed a comprehensive deep learning algorithm called “PrimateAI-3D”. It takes as input protein structures and fixed-species multiple ...
The landscape of tolerated genetic variation in humans and primates
The landscape of tolerated genetic variation in humans and primates · Abstract · Full Text · Info/History · Metrics · Supplementary material ...
The landscape of tolerated genetic variation in humans and primates
We show that these variants can be inferred to have nondeleterious effects in humans based on their presence at high allele frequencies in other primate ...
The landscape of tolerated genetic variation in humans and primates.
The landscape of tolerated genetic variation in humans and primates. ; Publication Type, Journal Article ; Year of Publication, 2023 ; Authors ...
The landscape of tolerated genetic variation in humans and primates
The landscape of tolerated genetic variation in humans and primates. / Gao, Hong; Hamp, Tobias; Ede, Jeffrey et al. In: Science, Vol. 380, No.
The landscape of tolerated genetic variation in humans and primates
By systematically cataloging common variants of nonhuman primates, we aimed to annotate these variants as being unlikely to cause human disease as they are ...
The landscape of tolerated genetic variation in humans and primates.
Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains.
The landscape of tolerated genetic variation in humans and primates
We show that these variants can be inferred to have nondeleterious effects in humans based on their presence at high allele frequencies in other primate ...
The landscape of tolerated genetic variation in humans and primates
The landscape of tolerated genetic variation in humans and primates · School of Geosciences · School of Biological Sciences. Research output: ...
The landscape of tolerated genetic variation in humans and primates
By systematically cataloging common variants of nonhuman primates, we aimed to annotate these variants as being unlikely to cause human disease ...
The landscape of tolerated genetic variation in humans and primates
To systematically decipher the effects of human genetic variants, we obtained whole-genome sequencing data for 809 individuals from 233 primate species and ...
The landscape of tolerated genetic variation in humans and primates
We show that these variants can be inferred to have nondeleterious effects in humans based on their presence at high allele frequencies in other ...
The landscape of tolerated genetic variation in humans and primates
Nonhuman primates provide unique evolutionary and comparative insight into the human phenotype. Genome assemblies are now… Une encyclopédie d'informations ...
The landscape of tolerated genetic variation in humans and primates
AbstractPersonalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance ...
The landscape of tolerated genetic variation in humans and primates
The landscape of tolerated genetic variation in humans and primates · About this Attention Score · Mentioned by · Citations · Readers on.
PRIMATE GENOMES. The landscape of tolerated genetic variation in humans and primates. Hong Gao†, Tobias Hamp†, Jeffrey Ede, Joshua G ...