The metabolic regulation of aging

The metabolic regulation of aging | Nature Medicine

Biochemical levels of tissue NAD+ seem to decline as a function of age in both model organisms and people. Although the basis for this age- ...

The metabolic regulation of aging - PubMed

Here we review the environmental and genetic manipulations that link cellular and organismal metabolism to aging. In particular, we explore how nutrients ...

Metabolic regulation of aging and age-related disease - PMC

Dr. Mattson's work on metabolic regulation of aging and age-related disease recapitulates the developmental ontogeny of neural circuits, ...

The metabolic regulation of aging - ETSU Libraries

Here we review the environmental and genetic manipulations that link cellular and organismal metabolism to aging. In particular, we explore how nutrients are ...

Metabolic regulation of aging and age-related disease - ScienceDirect

Aging is accompanied by reductions in insulin sensitivity and systemic glucose metabolism (Defronzo, 1981). Even within the normal physiological range, ...

Metabolic Control of Longevity: Cell

Multiple inborn defects in metabolic circuitries accelerate aging, whereas genetic loci linked to exceptional longevity influence metabolism.

Metabolic regulation of aging and age-related disease - ScienceDirect

In this historical review, we highlight Dr. Mattson's many contributions to understanding neurobiological responses to physical exercise and dietary ...

The metabolic regulation of aging - Semantic Scholar

How nutrients are sensed and how various intracellular energy nodes seem to coordinate distinct metabolic alterations linked to extended longevity are ...

Metabolic changes in aging humans: current evidence and ... - JCI

Adequate dietary protein, perhaps omega-3 fatty acids, and exercise training are the current mainstays of preventing metabolic abnormalities ...

Metabolic control of aging and metabolism - Nature

This collection aims to cover a broad range of themes linking metabolism and lifespan. We welcome studies interrogating basic cellular and ...

The metabolic regulation of aging - University of Massachusetts at ...

Here we review the environmental and genetic manipulations that link cellular and organismal metabolism to aging. In particular, we explore how nutrients are ...

The metabolic regulation of aging. - Abstract - Europe PMC

Here we review the environmental and genetic manipulations that link cellular and organismal metabolism to aging. In particular, we explore how nutrients ...

The biochemistry and cell biology of aging: metabolic regulation ...

Aging is characterized by increased risks for metabolic disorders, with age-associated degenerative diseases exhibiting varying degrees of mitochondrial ...

Metabolism - Center for Healthy Aging - Colorado State University

The following is a list of lifestyle strategies and tips that have been proven to powerfully impact the metabolic health of older adults.

The metabolic regulation of aging - ResearchGate

Mitochondrial and metabolic dysfunction have major roles in aging [7], since age progression is accompanied by metabolic changes, decline of mitochondrial ...

Recent Progress in Metabolic Signaling Pathways Regulating Aging ...

Several novel and unexpected concepts are emerging that will help to define the roles of altered metabolic control in the degenerative mechanisms of aging. This ...

Metabolic control and ageing: Trends in Genetics - Cell Press

Abstract. There appear to be multiple processes that are limiting for longevity and the associated mechanisms of ageing. Among these processes, metabolic ...

The metabolic regulation of aging - Toronto Metropolitan University

Here we review the environmental and genetic manipulations that link cellular and organismal metabolism to aging. In particular, we explore how nutrients are ...

Mathematical Modelling of Metabolic Regulation in Aging - MDPI

The underlying cellular mechanisms that characterize aging are complex and multifaceted. However, it is emerging that aging could be ...

Metabolic Regulation of Stem Cells in Aging

In this review, we focus on age-dependent changes in stem cell metabolism and dietary interventions used to modulate stem cell function in aging.