The mutational constraint spectrum quantified from variation ...
The mutational constraint spectrum quantified from variation ... - Nature
The mutational constraint spectrum quantified from variation in 141,456 humans · Main · A high-quality catalogue of variation · Identifying loss ...
The mutational constraint spectrum quantified from variation in ...
Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene ...
Addendum: The mutational constraint spectrum quantified ... - Nature
This analysis explores the extent of loss-of-function (LoF) tolerance in human disease genes. Databases of human population genetic variation, such as the ...
Addendum: The mutational constraint spectrum quantified from ...
This analysis explores the extent of loss-of-function (LoF) tolerance in human disease genes. Databases of human population genetic variation, ...
The mutational constraint spectrum quantified from variation in ...
Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that ...
The mutational constraint spectrum quantified from variation in ...
We classify human protein-coding genes along a spectrum representing tolerance to inactivation, validate this classification using data from model organisms ...
The mutational constraint spectrum quantified from variation in ...
Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: genes that ...
14.3. The mutational constraint spectrum quantified from variation in ...
Loss-of-function variants are mostly deleterious for health and development and are thus typically maintained at very low frequencies in human populations, but ...
(PDF) The mutational constraint spectrum quantified from variation ...
We classify human protein-coding genes along a spectrum that represents tolerance to inactivation, validate this classification using data from model organisms.
The mutational constraint spectrum quantified from variation in ...
SummaryGenetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic consequences of gene disruption: ...
The mutational constraint spectrum quantified from variation
Downloadable (with restrictions)! Genetic variants that inactivate protein-coding genes are a powerful source of information about the phenotypic ...
Author Correction: The mutational constraint spectrum quantified ...
[30] [31][32] In addition, we report a homozygous Astrin start-loss variant (heterozygous/homozygous individuals: 223/12 GH, 1761/25 gnomAD and ...
Author Correction: The mutational constraint spectrum quantified ...
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (Nature, (2020), 581, 7809, (434-443), 10.1038 ...
Author Correction: The mutational constraint spectrum quantified ...
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (Nature, (2020), 581, 7809, (434-443), 10.1038 ...
The mutational constraint spectrum quantified from variation in ...
The mutational constraint spectrum quantified from variation in 141456 humans (vol 581, pg 434, 2020)-article.
The mutational constraint spectrum quantified from variation in ...
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The mutational constraint spectrum quantified from variation in ...
Fingerprint. Dive into the research topics of 'The mutational constraint spectrum quantified from variation in 141,456 humans'. Together they ...
Author Correction: The mutational constraint spectrum quantified ...
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans (Nature, (2020), 581, 7809, (434-443), 10.1038/s41586-020-2308 ...
Author Correction: The mutational constraint spectrum quantified ...
(2021) Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humanS. Nature, 590 (7846), E53, [7809] ...
Author Correction: The mutational constraint spectrum ... - Altmetric
Author Correction: The mutational constraint spectrum quantified from variation in 141,456 humans. Overview of attention for article published in Nature ...