- The protease SPRTN and SUMOylation coordinate DNA|protein ...🔍
- SPRTN protease and SUMOylation coordinate DNA|protein ...🔍
- Mechanisms and Regulation of DNA|Protein Crosslink Repair ...🔍
- SPRTN patient variants cause global|genome DNA|protein crosslink ...🔍
- SUMOylation promotes protective responses to DNA‐protein ...🔍
- DNA–protein crosslink proteases in genome stability🔍
- DNA Structure|Specific Cleavage of DNA|Protein Crosslinks by the ...🔍
- SUMO orchestrates multiple alternative DNA|protein crosslink repair ...🔍
The protease SPRTN and SUMOylation coordinate DNA|protein ...
The protease SPRTN and SUMOylation coordinate DNA-protein ...
SUMOylation channels DPC repair toward SPRTN proteolysis, which is a safer pathway choice for DPC repair and prevention of genomic instability.
The protease SPRTN and SUMOylation coordinate DNA-protein ...
DPC SUMOylation prevents DNA double-strand break formation, HR activation, and potentially deleterious genomic rearrangements. In this way, ...
SPRTN protease and SUMOylation coordinate DNA-protein ...
DPC SUMOylation counteracts DPC ubiquitination, which promotes DNA breaks and the switch to HR. We propose that modification of DPCs by SUMO-1 ...
The protease SPRTN and SUMOylation coordinate DNA-protein ...
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Annamaria Ruggiano, Bruno Vaz, Susan Kilgas, Marta ...
The protease SPRTN and SUMOylation coordinate DNA-protein ...
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. by Annamaria Ruggiano, Bruno Vaz, Susan Kilgas, ...
The protease SPRTN and SUMOylation coordinate DNA-protein ...
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Ruggiano, Annamaria; Vaz, Bruno ...
Mechanisms and Regulation of DNA-Protein Crosslink Repair ...
The Protease SPRTN and SUMOylation Coordinate DNA-Protein Crosslink Repair to Prevent Genome Instability. Cell Rep. 37 (10), 110080. doi:10.1016/j.celrep ...
The protease SPRTN and SUMOylation coordinate DNA-protein ...
... The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability" accepted for publication in Cell
The protease SPRTN and SUMOylation coordinate DNA-protein ...
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability ... Authors: Annamaria Ruggiano; Bruno Vaz; Susan Kilgas ...
(PDF) SPRTN protease and SUMOylation coordinate DNA-protein ...
DPC modification by SUMO-1 favours SPRTN proteolysis as the preferred pathway for DPC repair. DPC SUMOylation counteracts DPC ubiquitination, ...
SPRTN patient variants cause global-genome DNA-protein crosslink ...
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Cell Rep. 37, 110080 (2021) ...
SPRTN protease and SUMOylation coordinate DNA-protein ... - OUCI
DPC modification by SUMO-1 favours SPRTN proteolysis as the preferred pathway for DPC repair. DPC SUMOylation counteracts DPC ubiquitination, which promotes DNA ...
The protease SPRTN and SUMOylation coordinate DNA-protein ...
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. by Annamaria Ruggiano, Bruno Vaz, ...
SUMOylation promotes protective responses to DNA‐protein ...
Whereas the budding yeast SprT protease Wss1 recognizes SUMO conjugates via SIMs, SPRTN recruitment to DNA damage sites in human cells is ...
DNA–protein crosslink proteases in genome stability - Nature
... SPRTN protease. Mol. Cell 80, 102 ... SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability.
DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the ...
We show that the DPC protease SPRTN displays strict DNA structure-specific activity. Strikingly, SPRTN cleaves DPCs at or in direct proximity to disruptions ...
SUMO orchestrates multiple alternative DNA-protein crosslink repair ...
SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. bioRxiv (2020). 2020.2002.2014.949289.
ubiquitin switch controls autocatalytic inactivation of the DNA ...
Abstract. Repair of covalent DNA–protein crosslinks (DPCs) by the metalloprotease SPRTN prevents genome instability, premature aging and ...
Targeting DNA-Protein Crosslinks via Post-Translational Modifications
The Protease SPRTN and SUMOylation Coordinate DNA-Protein Crosslink Repair to Prevent Genome Instability. Cell Rep. 37 (10), 110080. doi:10.1016/j.celrep ...
The Trinity of SPRTN Protease Regulation. - Abstract - Europe PMC
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. Ruggiano A, Vaz B, Kilgas S, Popović M, Rodriguez ...