The role of cell geometry and cell|cell communication in gradient ...

The role of cell geometry and cell-cell communication in gradient ...

We find that increasing the cell number can be detrimental for gradient sensing when the communication is weak and limited to nearest neighbour cells.

The role of cell geometry and cell-cell communication in gradient ...

Cells can measure shallow gradients of external signals to initiate and accomplish a migration or a morphogenetic process.

The role of cell geometry and cell-cell communication in gradient ...

Roughly speaking, in a LEGI model, the SNR increases with the number of cells N as long as cells on opposite edges can communicate with each other. The reason ...

The role of cell geometry and cell-cell communication in gradient ...

We find that increasing the cell number can be detrimental for gradient sensing when the communication is weak and limited to nearest neighbour ...

The role of cell geometry and cell-cell communication in gradient ...

Cellular communication has recently been suggested to play a key role in gradient sensing, and mathematical models with simplified cellular ...

The role of cell geometry and cell-cell communication in ... - PLOS

Fig 1. Computation of the SNR in a 2-dimensional LEGI model. We account for different orientations of the gradient by computing the SNR ...

The role of cell geometry and cell-cell communication in gradient ...

Here, we generalize the existing models to study the effects on gradient sensing of cell number, geometry and of long- versus short-range cellular communication ...

Communication is the key, also between cells.

The model posits the existence of two reporter molecules produced in response to the external signal: a local reporter that stays in the cell ...

Gradient sensing via cell communication | Request PDF

Experimental evidence lends support to the conjecture that cell-to-cell communication plays a role in the gradient sensing of chemical ...

Effects of 3D geometries on cellular gradient sensing and polarization

In this paper, we introduce a 3D reaction-diffusion model of interacting molecules in a single cell, and find that cell geometry has an important role ...

antisense. on X: "The role of cell geometry and cell-cell ...

The role of cell geometry and cell-cell communication in gradient sensing ...

Cells may possess hidden communication system - ScienceDaily

New research finds ion gradients across membranes form an information network for rapid cellular decision-making independent of DNA · Cell ...

Comparative analysis of cell–cell communication at single ... - Nature

These techniques generally function by aggregating ligand and receptor expression values for groups of cells to infer which groups of cells are ...

[PDF] Cell–cell communication enhances the capacity of cell ...

115 Citations · The role of cell geometry and cell-cell communication in gradient sensing · Collective Chemotaxis through Noisy Multicellular Gradient Sensing.

Chapter 9. Cell Communication

The ability to send messages quickly and efficiently enables cells to coordinate and fine-tune their functions. While the necessity for cellular communication ...

Cellular Dialogues: Cell-Cell Communication through Diffusible ...

How a group of mesoscopic numbers (hundreds to thousands) of cells, without pre-existing morphogen gradients and spatial organization, self- ...

Adjusting the range of cell–cell communication enables fine-tuning ...

This allows the cell type proportions to be controlled by a single model parameter. Cell–cell communication is realized by local and global ...

Cell–cell communication during collective migration - PNAS

Cell motility plays a critical role in many biological and medical processes, including wound healing, morphogenesis, and cancer metastasis.

Cell Signalling: Changing Shape Changes the Signal - ScienceDirect

Spatial gradients of signalling molecules are now believed to exist in a wide range of key cellular processes, such as cell division and cell ...

Gradient sensing via cell communication

Experimental evidence lends support to the conjecture that cell-to-cell communication plays a role in the gradient sensing of chemical ...