The role of lipid rafts in signalling and membrane trafficking in T ...

T cell activation induces a rapid compartmentalisation of signalling machinery into reorganised rafts that are used as platforms for the assembly of the ...

The association of glycosphingolipids with cholesterol forms membrane microdomains – lipid rafts – that are involved in specialised pathways of ...

The role of lipid rafts in signalling and membrane trafficking in T ...

The association of glycosphingolipids with cholesterol forms membrane microdomains – lipid rafts – that are involved in specialised pathways of protein/lipid ...

Role of lipid rafts in T cells - PubMed

Depending on the differentiation status of T cells, the lipid rafts seclude various protein receptors instrumental for the early T cell signaling, cytoskeleton ...

The role of lipid rafts in signalling and membrane trafficking in T ...

There are potential similarities between the specialised protein machinery underlying raft-mediated processes in T lymphocytes and polarised epithelial ...

The role of lipid rafts in T cell antigen receptor (TCR) signalling

The role of lipid rafts in signaling and membrane trafficking in T ...

As in epithelial cells, rafts are used also as vesicular carriers for membrane trafficking in T lymphocytes. Furthermore, there are potential similarities ...

Roles of lipid rafts in membrane transport - ScienceDirect.com

Cholesterol–sphingolipid microdomains (lipid rafts) are part of the machinery ensuring correct intracellular trafficking of proteins and lipids.

Lipid rafts: signaling and sorting platforms of cells and their roles in ...

Lipid rafts are defined as microdomains within the lipid bilayer of cellular membranes that assemble subsets of transmembrane or glycosylphosphatidylinisotol- ...

Role of Lipid Rafts in Pathogen-Host Interaction - A Mini Review

Lipid rafts, also known as microdomains, are important components of cell membranes and are enriched in cholesterol, glycophospholipids and receptors.

Full article: Foreword: lipid rafts/biophysics, cell signalling, trafficking ...

Although originally implicated in lipid and protein trafficking, lipid rafts now appear to be involved in a range of biological processes ...

Lipid rafts and little caves - Zajchowski - 2002 - FEBS Press - Wiley

By localizing all of the components of specific signalling pathways within a membrane compartment, lipid rafts could enable efficient and ...

Lipid raft - Wikipedia

Lipid rafts influence membrane fluidity and membrane protein trafficking, thereby regulating neurotransmission and receptor trafficking.

Lipid Rafts, Detergent-Resistant Membranes, and Raft Targeting ...

The best-studied raft targeting signal for transmembrane proteins is palmitoylation: usually linkage of two or more palmitoyl chains to the cytoplasmic domain, ...

The role of lipid rafts n membrane trafficking in t lymph 2001 | PDF

The role of lipid rafts n membrane trafficking in t lymph 2001 ... 3958 JOURNAL OF CELL SCIENCE 114 (22) Fig. 1. Model of lipid.

Lipid rafts in immune signalling: current progress and future ...

Lipid raft-associated adaptor proteins LAT and non-T cell activation linker (NTAL) act as the positive and negative regulators of FcεRI ...

Emerging Themes in Lipid Rafts and Caveolae - Cell Press

As a consequence, regulation of caveolin expression may indirectly affect signaling mechanisms by its cholesterol-trafficking role. Besides caveolins, several ...

LIPID RAFTS AND SIGNAL TRANSDUCTION - Biology

Role of membrane organization and membrane domains in endocytic lipid trafficking. ... The role of membrane- associated adaptors in T cell receptor signalling.

Lipids as Organizers in Cell Membranes: Lipid Sorting and Lipid Rafts

Lipid rafts form when cholesterol and sphingolipids are concentrated in the plasma membrane. Kai Simons explains that lipid sorting can organize proteins in ...

The Role of Lipid Rafts in Signal Transduction and Synaptic ...

Compartmentalization of proteins within the cell plays a fundamental role in the spatial and temporal organization of intracellular signaling systems.