The role of long noncoding RNAs in the diagnosis

The role of long noncoding RNAs in the diagnosis, prognosis and ...

LncRNAs are nonprotein-coding RNAs that are approximately 200 nucleotides long and play important roles in the regulation, metabolism and ...

Roles of long noncoding RNAs in human inflammatory diseases

Increasing evidence suggests that lncRNAs are key players in the inflammatory response, making it a potential therapeutic target for various diseases.

The role of long noncoding RNAs in cancer: the dark matter matters

Using next-generation sequencing, thousands of long noncoding RNAs (lncRNAs) have been identified as abnormally altered in the cancer genome or ...

The role of long noncoding RNAs in hepatocellular carcinoma

These vital roles and unique properties of lncRNAs suggest their potential clinical value in the HCC diagnosis and treatment. In this review ...

Long Non-coding RNAs in Cancer: Implications for Diagnosis ...

Studies have shown that lncRNAs with high specificity and accuracy have the potential to become biomarkers in cancers. LncRNAs can be ...

Gene regulation by long non-coding RNAs and its biological functions

Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene ...

Article The long non-coding RNAs, a new cancer diagnostic and ...

With advancements in cancer transcriptome profiling and accumulating evidence supporting lncRNA function, lncRNAs are emerging as new factors in the cancer ...

The Emerging Roles of Long Noncoding RNAs as Hallmarks of ...

Furthermore, increasing attention has been given to lncRNAs as biomarkers for early cancer diagnosis, prognosis, and therapeutic response ...

The functional role of long non-coding RNA in human carcinomas

Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive ...

Unravelling the role of long non-coding RNAs in prostate carcinoma

The growing demand for finding a permanent cure for PCa has resulted in their overdiagnosis, thereby increasing the chances of utilising lncRNAs as promising ...

Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and ...

Furthermore, as the enormous spectrum of long noncoding RNAs potentially opens up new avenues for diagnosis and prevention of heart failure, we ...

Long Noncoding RNA and Cancer: A New Paradigm - AACR Journals

In particular, long noncoding RNAs (ncRNAs that are >200 nt long) play key roles in regulating chromatin dynamics, gene expression, growth, ...

Long Noncoding RNAs as Novel Biomarkers Have a Promising ...

We evaluate the diagnostic performance of lncRNAs as tumor biomarkers. However, the biological functions and the mechanisms of circulating ...

The roles of long noncoding RNAs in myocardial pathophysiology

LncRNAs have a key function in the alleviation of myocardial infarction (MI) injury and myocardial ischemia–reperfusion injury. During cardiac hypertrophy (CH) ...

From Discovery to Function: The Expanding Roles of Long ...

Abstract. Long noncoding RNAs (lncRNAs) are a relatively poorly understood class of RNAs with little or no coding capacity transcribed from a set of incomp.

Long non-coding RNAs: Biogenesis, functions, and ... - Cell Press

contribute to the development of better diagnostics and treat- ments for GC. INTRODUCTION. Gastric cancer (GC) is one of the most common malignant tumors of the ...

Roles and Mechanisms of the Long Noncoding RNAs in Cervical ...

They have been associated with several disease-related processes such as cell growth, cell proliferation, cell survival, metastasis and invasion as well as ...

The role of long noncoding RNAs in the diagnosis, prognosis and ...

The therapeutic, diagnostic and prognostic roles of lncRNAs in AML are discussed and future insights are provided that will contribute to studies targeting ...

Molecular mechanisms of long noncoding RNAs and their role in ...

LncRNAs are long non-coding regulatory RNAs that are longer than 200 nucleotides. One of the major functions of lncRNAs is the regulation of specific gene ...

Role of long noncoding RNAs in malignant disease (Review)

Long noncoding RNAs (lncRNAs) are endogenous transcribed RNA molecules without protein-coding potential, ranging between 200 and 100,000 nt ...