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The roles of ferroptosis in cancer


Ferroptosis in cancer: from molecular mechanisms to therapeutic ...

Ferroptosis induction in tumor suppression. Ferroptosis appears to function as an innate mechanism for tumor suppression, mediating the ...

The roles of ferroptosis in cancer: Tumor suppression ... - Cell Press

Induction of ferroptosis not only suppresses tumor growth but also holds potential for augmenting immunotherapy responses and surmounting resistance to existing ...

Broadening horizons: the role of ferroptosis in cancer - Nature

The discovery of regulated cell death processes has enabled advances in cancer treatment. In the past decade, ferroptosis, an iron-dependent ...

What is the role of ferroptosis in cancer?

Recent studies reveal that ferroptosis plays a significant role in tumor suppression, giving us new opportunities for cancer treatment.

The roles of ferroptosis in cancer: Tumor suppression ... - PubMed

In cancer treatment, the recurrent challenge of inducing apoptosis through conventional therapeutic modalities, often thwarted by therapy ...

Ferroptosis in cancer therapy: a novel approach to reversing drug ...

Extensive studies suggest that ferroptosis plays a pivotal role in tumor suppression, thus providing new opportunities for cancer therapy.

The roles of ferroptosis in cancer: Tumor suppression ... - Cell Press

Right: Role of ferroptosis in immunosuppression. Ferroptotic cancer cells can release certain products of phospholipid peroxidation, impairing ...

The roles of ferroptosis in cancer: Tumor suppression, tumor ...

Induction of ferroptosis not only suppresses tumor growth but also holds potential for augmenting immunotherapy responses and surmounting ...

The Role of Ferroptosis in Cancer Development and Treatment ...

Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell death, which is a distinct regulated cell death ...

Targeting ferroptosis for cancer therapy: exploring novel strategies ...

Ferroptosis roles as a double-edged sword either suppressing or promoting tumor progression with the release of multiple signaling molecules in the tumor ...

The role of ferroptosis in human diseases | Proteintech Group

One of the most well-studied areas of ferroptosis research is its role in cancer. Ferroptosis has been shown to have both pro-tumor and anti-tumor effects. It ...

The Role of Ferroptosis in Cancer Development and Treatment ...

Ferroptosis is a process driven by accumulated iron-dependent lipid ROS that leads to cell death, which is a distinct regulated cell death comparing to other ...

Molecular mechanisms of ferroptosis and its role in cancer therapy

Abstract. Ferroptosis is a newly defined programmed cell death process with the hallmark of the accumulation of iron-dependent lipid peroxides.

Ferroptotic therapy in cancer: benefits, side effects, and risks

Extensive studies suggest that ferroptosis plays a pivotal role in tumor suppression, thus providing new opportunities for cancer therapy.

Cancer: The role of iron and ferroptosis - ScienceDirect.com

We discuss the role of iron in cancer, and ferroptosis, a new form of iron-regulated cell death triggered by increased iron and peroxidation of lipids.

Exploring Ferroptosis-Inducing Therapies for Cancer Treatment

However, challenges, including the lack of distinctive ferroptosis markers and the intricate role of ferroptosis within the tumor ...

Role of ferroptosis in cancer - YouTube

Our study published in Nature explores how inhibiting ferroptosis, a type of programmed cell death that occurs exclusively in the tumour ...

The function and mechanism of ferroptosis in cancer | Apoptosis

Abstract. Ferroptosis is a newly defined form of regulated cell death (RCD) characterized by iron overload, lipid reactive oxygen species (ROS) ...

Ferroptosis: the vulnerability within a cancer monster - JCI

As such, ferroptosis inducers, including GPX4 inhibitors, have some specificity in targeting cancer cells while sparing normal cells. Indeed, ...

A guide to ferroptosis in cancer - Yapici - 2024 - FEBS Press - Wiley

Therefore, it is not surprising that recent findings hint at the pivotal role of ferroptosis in cancer cell biology [[107-110]]. Intriguingly, ...