The tumor immune microenvironment in pancreatic cancer and its ...

Elucidating the mechanisms by which CAFs, microbiomes, and TDEs are involved in the tumorigenesis of PC will be helpful for developing novel ...

The Immune Microenvironment in Pancreatic Cancer - PubMed

The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment.

Tumour microenvironment of pancreatic cancer: immune landscape ...

... immune evasion. At present, there is much interest in classifying pancreatic cancer according to its morphologic, genetic and immunologic ...

The tumor immune microenvironment in pancreatic cancer and its ...

Owing to this TME, PC can inhibit the immune system and resist immunotherapy. The TME, especially of PC, contains a high number of tumor- ...

Tumor immune microenvironment-based therapies in pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor immune microenvironment (TIME) formed by ...

Pancreatic cancer tumor microenvironment is a major therapeutic ...

The physical barrier and immune counterbalance in the tumor microenvironment (TME) make PDAC an immunologically cold tumor. To convert PDAC into an ...

The tumor immune microenvironment in resected treatment-naive ...

In conclusion, our study unveiled a distinctive yet intricate TIME associated with prolonged survival in pancreatic cancer. This profile ...

The Tumor Immune Microenvironment in Pancreatic Ductal ... - MDPI

Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic tumor and is associated with poor prognosis and treatment response.

The tumor immune microenvironment in resected treatment-naive ...

Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy known for its aggressiveness and lethality and ranks as the third cause ...

655 Dissecting pancreatic cancer tumor-immune microenvironment ...

Background Pancreatic ductal adenocarcinoma (PDAC) often fails to respond to immune therapies due to various factors, including the role of Epithelial to ...

Innate and adaptive immune-directed tumour microenvironment in ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid tumours in humans. It is the most frequent form of pancreatic cancer, 90% ...

Dynamic profiling of immune microenvironment during pancreatic ...

Pancreatic ductal adenocarcinoma (PDAC) has little response to immune checkpoint inhibitors. An in-depth understanding of the immune ...

The Immune Microenvironment in Pancreatic Cancer - MDPI

The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment. In this regard, pancreatic ...

Immune microenvironment and immunotherapy in pancreatic cancer

Since Tregs' primary function is to regulate immune system function, its role in the tumor immune microenvironment is also considered to negatively regulate ...

Epigenetic and Transcriptional Control of the Epidermal Growth ...

... the Tumor Immune Microenvironment in Pancreatic Cancer. Jinyang Li. ORCID logo ... This study defines an epigenetic–transcriptional mechanism by which tumor cells ...

Impact of the tumor immune microenvironment on the outcome of ...

However, the distribution of these cells and their associated cytokines in the tumor microenvironment of pancreatic cancer (PC) are not yet ...

The tumor immune microenvironment in pancreatic ductal ...

Key elements of its heterogeneity stem from cancer-associated fibroblasts (CAFs), endothelial cells, and numerous subsets of immune cells (Figure 1).

Tumor Microenvironment in Pancreatic Cancer Pathogenesis and ...

Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment with remarkable cellular and spatial heterogeneity ...

Immune cell infiltration as an indicator of the immune ... - Nature

Pancreatic cancer (pancreatic ductal carcinoma (PDC)) is the fourth and fifth leading cause of cancer-related death in the United States and ...

Tumor immune microenvironment-based therapies in pancreatic ...

AbstractPancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor immune microenvironment (TIME) formed by interactions ...