Therapeutic Potential of Long Non|Coding RNAs of HIV|1

Therapeutic Potential of Long Non-Coding RNAs of HIV-1, SARS ...

Accumulated evidence indicates that lncRNAs regulate antiviral immune responses mainly by transcription of IFN regulatory factors 1 (IRF1) and 4 (IRF4).

Role of long noncoding RNA in regulating HIV infection—a ... - NCBI

... potential therapeutic applications of lncRNAs in combatting HIV. A deeper understanding of how lncRNAs modulate HIV gene transcription holds ...

Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation ...

... lncRNAs in disease and possible strategies for the therapeutic targeting of HIV-1. 2. HIV-1 Transcribed Long Non-Coding RNA. LncRNA ...

Long noncoding RNA NRON contributes to HIV-1 latency ... - Nature

Here we investigated the role of lncRNAs in HIV-1 latent infection, and have identified a lncRNA NRON, which potentially contributes to HIV-1 ...

Roles and potential applications of lncRNAs in HIV infection

therapeutic target for immunotherapy. Postler et al. (2017). lncRNAs, long non-coding RNAs; cART, combination antiretroviral therapy; NA, not available; HAART ...

Roles of lncRNAs in the transcription regulation of HIV-1

Long noncoding RNAs (LncRNAs) is a class of RNA molecules that are more than 200bp but cannot be translated into proteins. More and more studies have proved ...

Discovery of long non-coding RNAs in naïve CD4 + T cells in ...

In conclusion, our study emphasizes the need for further exploration of lncRNAs as potential biomarkers and therapeutic targets in HIV-1- ...

Non-Coding RNAs in HIV Infection, NeuroHIV, and Related ... - MDPI

The review also explores potential diagnostic and therapeutic implications for modulating NeuroHIV pathways. 2. Non-Coding (nc)RNAs. ncRNAs encompass a diverse ...

Gene regulation by long non-coding RNAs and its biological functions

Box 1 Long non-coding RNAs and genome integrity ... Long non-coding RNA TINCR as potential biomarker and therapeutic target for cancer.

MicroRNAs and long non-coding RNAs during transcriptional ...

We further discuss treatment strategies using ncRNAs for HIV and HTLV long remission, reactivation or possible cure. Background. The cellular ...

The Function and Therapeutic Potential of Long Non-coding RNAs ...

... lncRNAs (particularly circular lncRNAs [circRNAs]) (Figure 1).10, 11 In this review, we do not address in detail the lncRNAs mechanisms of action but ...

The potential therapeutic applications of long non-coding RNAs

Regulatory ncRNAs are largely split into two classes: small non-coding (sncRNAs) RNAs of < 200 nucleotides in length and lncRNAs of > 200 nucleotides [Figure 1] ...

The potential of long noncoding RNA therapies

... RNA therapies and mRNA vaccines (Box 1). These advances have also potentiated the development of noncoding RNA (ncRNA) as a new class of therapy [1]. Over ...

Long Noncoding RNA: Regulatory Mechanisms and Therapeutic ...

Table 1 lncRNAs as potential biomarker for sepsis and sepsis-induced organ dysfunctions. Furthermore, several studies suggested that lncRNA ...

Non-coding RNAs in human health and disease: potential function ...

Non-coding RNA therapeutics. Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), as well as other types of non-coding RNAs (ncRNAs), are ...

The long non-coding RNAs, a new cancer diagnostic and ...

... potential therapeutic targets. As more examples of regulation by lncRNA are ... potential roles in both oncogenic and tumor-suppressive pathways (Table 1).

Therapeutic potential of extracellular vesicle‐associated long ...

Both extracellular vesicles (EVs) and long noncoding RNAs (lncRNAs) have been increasingly investigated as biomarkers, pathophysiological ...

Therapeutic Potential of Long Non-Coding RNAs of HIV-1, SARS ...

Long non-protein coding RNAs (lncRNAs, predicted to be up to 200000 in the human genome) are nucleic acids of more than 200 nucleotides that not only play ...

The Long Noncoding RNA HEAL Regulates HIV-1 Replication ...

... treatment, suggesting HEAL as a potential therapeutic target to cure HIV-1/AIDS. INTRODUCTION. Human immunodeficiency virus type 1 (HIV-1) is a pathogenic ...

The Function and Therapeutic Potential of Long Non-coding RNAs ...

... 1. Table 1List of Available Databases on lncRNAs. Database, What, Species, No. of lncRNAs, Last Update, Association with Function, Association ...