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Therapeutic Targeting of the Tumor Microenvironment


Therapeutic Targeting of the Tumor Microenvironment

This review provides a comprehensive analysis of the current therapies targeting the TME, combining a discussion of the underlying basic biology with clinical ...

Therapeutic Targeting of the Tumor Microenvironment - PubMed

Strategies to therapeutically target the tumor microenvironment (TME) have emerged as a promising approach for cancer treatment in recent years due to the ...

Therapeutic targeting of the tumor microenvironment - ScienceDirect

Focus. Therapeutic targeting of the tumor microenvironment · Introduction · The tumor stroma: An active player in cancer · Targeting the tumor vasculature: ...

Tumor microenvironment as a therapeutic target in cancer - PMC

Tumor microenvironment denotes the non-cancerous cells and components presented in the tumor, including molecules produced and released by them.

Therapeutic targeting of the tumor microenvironment: Cancer Cell

These strategies include targeting the tumor cells themselves, with traditional therapies such as chemotherapy and radiotherapy (which will also kill normal ...

Targeting the tumor microenvironment: Potential strategy for cancer ...

Chemotherapy, surgery and radiation therapies are typical therapeutic modalities to treat cancer depending on the disease stage [1]. Since the development of ...

Therapeutic targeting of the tumor microenvironment: Cancer Cell

One advantage of therapies targeting the microenvironment is that these nontumor cells are presumably genetically stable, which is in contrast to tumor cells ...

Therapeutic targeting of the hypoxic tumour microenvironment - Nature

Hypoxia is prevalent in human tumours and contributes to microenvironments that shape cancer evolution and adversely affect therapeutic ...

Therapeutic Targeting of Tumor Cells and Tumor Immune ... - Frontiers

Therapeutic targeting of tumor vulnerabilities is emerging as a key area of research. This review is focused on exploiting the vulnerabilities of tumor cells ...

Tumor microenvironment: barrier or opportunity towards effective ...

Tumor microenvironment (TME) is a specialized ecosystem of host components, designed by tumor cells for successful development and metastasis of tumor.

Targeting Tumor Microenvironment for Cancer Therapy - MDPI

A big effort has been made to develop new therapeutic strategies towards a more efficient targeting of TME.

Targeting the Tumor Microenvironment for Cancer Therapy

The targeting of the tumor microenvironment to encapsulate or destroy cancer cells in their local environment has become mandatory.

Targeting the tumor microenvironment: removing obstruction to ...

Accordingly, novel targets within the TME have been uncovered that can help direct and improve the actions of various cancer therapies, notably immunotherapies ...

The updated landscape of tumor microenvironment and drug ...

Hypoxic niche and immune microenvironment are regarded as two vital specialized microenvironments that can reprogram cancer biology in various ...

Targets of tumor microenvironment for potential drug development

The first-in-class drug, ibrutinib, has been especially transformative, paving the way for a potential era of chemotherapy-free management in B ...

[PDF] Therapeutic Targeting of the Tumor Microenvironment.

The most advanced TME-directed therapies, which have either been clinically approved or are currently being evaluated in trials, including immunotherapies, ...

Therapeutic targeting of the tumor microenvironment - Revvity

Understanding How Tumor and Host Cells Interact to Support Tumor Development and Therapeutic Resistance.

Therapeutic Targeting of the Tumor Microenvironment - ResearchGate

Targeted therapy for tumors, a therapeutic approach that selectively targets tumor cells while sparing other cells in the TME, has emerged as a promising and ...

Therapeutic Targeting of the Tumor Microenvironment. - Abstract

Strategies to therapeutically target the tumor microenvironment (TME) have emerged as a promising approach for cancer treatment in recent years due to the ...

Targeting Tumor and Tumor Microenvironment Vulnerabilities

Authors posit that mitochondria-targeted drugs combined with standard-of-care chemotherapy, radiation therapy, and immunotherapy are likely ...